BACLESTA TAB

About

BACLESTA TAB contains Baclofen, a centrally acting skeletal muscle relaxant. It functions as a gamma-aminobutyric acid (GABA) analogue, specifically acting as an agonist at GABA-B receptors. This action primarily occurs in the spinal cord, where it inhibits both monosynaptic and polysynaptic reflexes. By hyperpolarizing afferent terminals and inhibiting the release of excitatory neurotransmitters, Baclofen reduces the frequency and severity of muscle spasms, clonus, and associated pain.

BACLESTA TAB is particularly effective in managing spasticity arising from various neurological conditions. Its ability to decrease muscle hypertonicity helps improve patient mobility, facilitates rehabilitation, and enhances overall daily functioning, providing significant relief from the debilitating symptoms of severe muscle spasticity.

Uses

• Management of spasticity from multiple sclerosis
• Relief of spasticity from spinal cord injuries
• Treatment of spasticity in cerebral palsy
• Reduction of muscle spasms in other neurological disorders

Directions For Use

Take orally with food or milk to minimize gastrointestinal upset. Start with a low dose and gradually increase as directed by your doctor.

Benefits

• Significantly reduces muscle spasms and clonus
• Alleviates associated pain and discomfort
• Improves range of motion and mobility
• Facilitates physical therapy and rehabilitation
• Enhances overall daily functional abilities
• May improve sleep quality by reducing nocturnal spasms

Side Effects

• Drowsiness
• Dizziness
• Weakness
• Nausea
• Headache
• Confusion
• Fatigue
• Insomnia
• Hypotension
• Urinary frequency
• Constipation
• Withdrawal symptoms if stopped abruptly

Safety Measures

• Alcohol - Avoid alcohol consumption as it can significantly enhance the central nervous system depressant effects of Baclofen, leading to increased drowsiness and dizziness.
• Pregnancy - Consult your doctor. Use only if the potential benefits justify the potential risks to the fetus.
• Breastfeeding - Consult your doctor. Small amounts of Baclofen may pass into breast milk; use with caution.
• Liver - Use with caution in patients with hepatic impairment; monitor liver function during prolonged therapy.
• Kidney - Dose adjustment is required in patients with renal impairment as Baclofen is primarily excreted by the kidneys.
• Lung - Use with caution in patients with respiratory impairment, as Baclofen can cause respiratory depression, especially at higher doses.

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