Bdpoma 2mg Capsule

About

Bdpoma 2mg Capsule contains Pomalidomide, an immunomodulatory drug with direct anti-tumor, anti-angiogenic, and immunomodulatory properties. It works by inhibiting the proliferation and inducing apoptosis of hematopoietic tumor cells, enhancing T cell and natural killer (NK) cell-mediated immunity, and inhibiting the production of pro-inflammatory cytokines. Pomalidomide is primarily used in the treatment of multiple myeloma, particularly in patients who have received prior therapies and are refractory to other treatments. Its multifaceted mechanism of action helps to disrupt the growth and survival pathways of cancer cells, making it a valuable therapeutic option in advanced stages of the disease, often in combination with other agents.

Uses

• Relapsed/refractory Multiple Myeloma
• HIV-associated Kaposi's Sarcoma (off-label)
• Myelodysplastic Syndromes (off-label)
• Certain Lymphomas (investigational)

Directions For Use

Take orally once daily with water, at the same time each day, with or without food. Do not open, break, or chew capsules.

Benefits

• Effective in relapsed/refractory multiple myeloma
• Improves overall survival in combination therapies
• Offers a treatment option for patients resistant to other drugs
• Has immunomodulatory and anti-angiogenic effects
• Can be part of a multi-drug regimen
• Generally manageable side effect profile

Side Effects

• Myelosuppression (neutropenia, thrombocytopenia)
• Fatigue and asthenia
• Constipation
• Nausea and vomiting
• Diarrhea
• Peripheral neuropathy
• Deep vein Thrombosis (DVT)
• Pulmonary Embolism (PE)
• Rash and pruritus
• Dyspnea (shortness of breath)
• Muscle spasms
• Dizziness

Safety Measures

• Alcohol - Avoid excessive alcohol due to potential for increased fatigue and liver strain.
• Pregnancy - Contraindicated. Causes severe birth defects. Strict pregnancy prevention program required.
• Breastfeeding - Contraindicated. Excreted in breast milk and can harm the infant.
• Liver - Use with caution; dose adjustment may be necessary in patients with hepatic impairment.
• Kidney - Use with caution; dose adjustment may be necessary in patients with renal impairment.
• Lung - Monitor for pulmonary events, including dyspnea and interstitial lung disease, though rare.

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