BIAPRIDE INJECTION 1 S

About

Biapride Injection is an atypical antipsychotic medication primarily used in the management of various psychiatric conditions. It exerts its therapeutic effects by selectively blocking dopamine D2 and D3 receptors in the brain, particularly in the mesolimbic pathway, which helps to alleviate positive symptoms of psychosis such as hallucinations and delusions. Additionally, it may have some affinity for serotonin 5-HT2A receptors, contributing to its broader spectrum of action and potentially improving negative symptoms and cognitive function with a lower propensity for extrapyramidal side effects compared to older antipsychotics.

Its injectable form allows for rapid onset of action, making it suitable for acute management in clinical settings where oral administration may not be feasible or rapid symptom control is required. This formulation ensures consistent drug levels, which is crucial for stabilizing patients experiencing acute psychotic episodes or severe agitation, thereby facilitating quicker symptom resolution and improved patient management in critical situations.

Uses

• Acute management of schizophrenia and related psychotic disorders.
• Treatment of acute manic episodes associated with bipolar disorder.
• Management of severe agitation and behavioral disturbances.
• Adjunctive therapy for certain mood disorders.

Directions For Use

Administer intramuscularly or intravenously as directed by a healthcare professional. Dosage and frequency depend on the patient's condition and response.

Benefits

• Effective in reducing psychotic symptoms.
• May improve mood and reduce agitation.
• Potentially lower risk of certain motor side effects.
• Rapid onset of action in injectable form.
• Helps stabilize acute psychiatric crises.
• Can be used when oral medication is not possible.

Side Effects

• Drowsiness or sedation
• Dizziness
• Headache
• Nausea
• Vomiting
• Weight gain
• Dry mouth
• Constipation
• Blurred vision
• Restlessness (akathisia)
• Muscle stiffness (extrapyramidal symptoms)
• Increased prolactin levels

Safety Measures

• Alcohol - Avoid alcohol consumption as it can intensify central nervous system depression and increase the risk of adverse effects like drowsiness and dizziness.
• Pregnancy - Use with caution; potential risks to the fetus should be weighed against the benefits. Consult a doctor.
• Breastfeeding - Not recommended as the medication may pass into breast milk and affect the infant. Seek medical advice.
• Liver - Use with caution in patients with hepatic impairment; dosage adjustments may be necessary. Regular monitoring is advised.
• Kidney - Use with caution in patients with renal impairment; dosage adjustments may be required. Monitor kidney function.
• Lung - Generally safe for lung conditions, but monitor for respiratory depression if co-administered with other CNS depressants.

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