Calutide 50mg Tablet

About

Bicalutamide is a non-steroidal antiandrogen used in the treatment of prostate cancer. It works by blocking the action of androgens (male hormones like testosterone) at receptor sites in prostate cancer cells. Androgens stimulate the growth of prostate cancer, so by blocking their effects, bicalutamide helps to slow down or stop the progression of the disease. This mechanism of action is crucial in hormone-sensitive prostate cancer, where androgen deprivation is a primary therapeutic strategy.

It is often used in combination with luteinizing hormone-releasing hormone (LHRH) analogues or surgical castration as part of maximal androgen blockade (MAB) therapy for advanced prostate cancer. It can also be used as monotherapy in some cases, particularly for locally advanced disease. Regular monitoring of prostate-specific antigen (PSA) levels and liver function is important during treatment to assess efficacy and manage potential toxicities.

Uses

• Advanced prostate cancer (in combination with LHRH analogue)
• Locally advanced prostate cancer (as monotherapy or adjuvant)
• Metastatic prostate cancer
• Non-metastatic castration-resistant prostate cancer

Directions For Use

Take orally once daily with or without food. Follow your doctor's instructions regarding dosage and duration.

Benefits

• Effective in treating prostate cancer.
• Helps to reduce tumor growth.
• Can improve disease control.
• Available as an oral tablet.
• Can be used in combination therapy.
• May improve quality of life for patients.

Side Effects

• Hot flashes
• Breast pain and gynecomastia (breast enlargement)
• Nausea
• Diarrhea
• Fatigue
• Liver enzyme elevation
• Anemia
• Rash
• Dizziness
• Peripheral edema
• Weight gain
• Sexual dysfunction

Safety Measures

• Alcohol - Limit alcohol intake, as it may increase the risk of liver side effects.
• Pregnancy - Not applicable for male patients. For women, it is contraindicated due to potential harm to a male fetus.
• Breastfeeding - Not applicable for male patients. For women, it is contraindicated.
• Liver - Use with caution in patients with liver impairment; regular monitoring of liver function is essential.
• Kidney - Generally considered safe in kidney impairment, but use with caution and monitor.
• Lung - Rare cases of interstitial lung disease have been reported; monitor for respiratory symptoms.

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