CARCA CR 10MG 15

About

Carvedilol CR 10mg is a non-selective beta-adrenergic blocker with concomitant alpha-1 adrenergic blocking activity, used in the management of various cardiovascular conditions. Its dual action provides a unique pharmacological profile: beta-blockade reduces heart rate and myocardial contractility, while alpha-1 blockade leads to vasodilation, reducing peripheral vascular resistance. This combined effect results in effective blood pressure lowering and improved cardiac function, particularly beneficial in heart failure.

The controlled-release formulation ensures a steady therapeutic level over 24 hours, allowing for once-daily dosing and minimizing fluctuations in drug concentration. It also possesses antioxidant and anti-proliferative properties, contributing to its organ-protective effects, especially in the heart and kidneys. This makes it a valuable agent for patients with hypertension, angina, and chronic heart failure, improving symptoms and prognosis.

Uses

• Management of essential hypertension.
• Treatment of chronic stable angina.
• Management of stable symptomatic chronic heart failure.
• Improvement of left ventricular function post-myocardial infarction.

Directions For Use

Take orally once daily in the morning with food, as directed by your physician. Do not crush or chew the tablet.

Benefits

• Effectively lowers blood pressure.
• Improves symptoms and survival in heart failure.
• Reduces heart rate and workload.
• Provides antioxidant and anti-inflammatory effects.
• Offers sustained 24-hour action.
• Reduces risk of cardiovascular events.

Side Effects

• Dizziness or lightheadedness
• Fatigue or weakness
• Bradycardia (slow heart rate)
• Hypotension (low blood pressure)
• Nausea or diarrhea
• Shortness of breath
• Weight gain (in heart failure)
• Peripheral edema
• Headache
• Masking of hypoglycemia symptoms
• Sexual dysfunction
• Bronchospasm (especially in susceptible individuals)

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can enhance the blood pressure-lowering effect and increase dizziness.
• Pregnancy - Use only if the potential benefit justifies the potential risk to the fetus; consult a healthcare provider.
• Breastfeeding - Carvedilol passes into breast milk; monitor the infant for signs of beta-blockade.
• Liver - Contraindicated in patients with clinically manifest hepatic impairment due to extensive liver metabolism.
• Kidney - Generally safe in kidney disease, but monitor closely in severe renal impairment.
• Lung - Contraindicated in patients with bronchial asthma or severe COPD due to non-selective beta-blocking activity.

Disclaimer

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