CILNY 10MA 10S

About

Cilnidipine is a dihydropyridine calcium channel blocker primarily used in the management of hypertension. It acts by inhibiting the influx of calcium ions into vascular smooth muscle cells, leading to vasodilation and a reduction in peripheral vascular resistance. Unlike some other calcium channel blockers, cilnidipine also blocks N-type calcium channels in sympathetic nerve endings, which can help to suppress sympathetic overactivity, a common contributor to hypertension.

This dual action contributes to its effective blood pressure-lowering effects and may offer additional benefits in terms of organ protection, particularly in the kidneys. Its sustained action allows for once-daily dosing, providing consistent blood pressure control throughout the day and night, which is crucial for preventing cardiovascular events. It is generally well-tolerated and can be a suitable option for various hypertensive patients.

Uses

• Management of essential hypertension.
• Treatment of isolated systolic hypertension.
• Reduction of cardiovascular risk.
• Improvement of blood pressure control.

Directions For Use

Take orally once daily, preferably in the morning, with or without food, as directed by your physician.

Benefits

• Effectively lowers blood pressure.
• Reduces peripheral vascular resistance.
• Suppresses sympathetic overactivity.
• Provides sustained 24-hour blood pressure control.
• May offer renoprotective effects.
• Generally well-tolerated.

Side Effects

• Headache
• Dizziness
• Flushing
• Peripheral edema (swelling of ankles/feet)
• Palpitations
• Nausea or stomach discomfort
• Fatigue
• Gingival hyperplasia (gum overgrowth)
• Hypotension (low blood pressure)
• Rash
• Bradycardia (rare)
• Increased liver enzymes (rare)

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can enhance the blood pressure-lowering effect and increase dizziness.
• Pregnancy - Use only if the potential benefit justifies the potential risk to the fetus; consult a healthcare provider.
• Breastfeeding - Not recommended during breastfeeding as it may pass into breast milk; consult a doctor.
• Liver - Use with caution in patients with liver impairment; dose adjustment may be necessary.
• Kidney - Generally safe in kidney disease, but monitor closely in severe renal impairment.
• Lung - Generally considered safe for patients with lung conditions as it does not directly affect respiratory function.

Disclaimer

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