About

This medication combines Amlodipine, a dihydropyridine calcium channel blocker, with Telmisartan, an angiotensin II receptor blocker (ARB), to provide comprehensive management for hypertension. Amlodipine works by relaxing blood vessels, reducing peripheral resistance and lowering blood pressure, while also improving blood flow to the heart. Telmisartan blocks the action of angiotensin II, a potent vasoconstrictor, leading to further vasodilation and a reduction in blood pressure. The synergistic action of these two agents targets different pathways involved in blood pressure regulation, offering enhanced antihypertensive efficacy compared to monotherapy. This combination is particularly beneficial for patients whose blood pressure is not adequately controlled with either agent alone, providing sustained 24-hour blood pressure control and reducing the risk of cardiovascular events.

Uses

Management of essential hypertension.
Treatment of high blood pressure when single-drug therapy is inadequate.
Reduction of cardiovascular risk in hypertensive patients.
Long-term blood pressure control.

Directions For Use

Take one tablet orally once daily, with or without food, as prescribed by your doctor. Swallow whole with water.

Benefits

Achieves significant blood pressure reduction.
Provides dual-action antihypertensive therapy.
Offers sustained 24-hour blood pressure control.
Reduces the incidence of cardiovascular events.
Improves patient adherence with once-daily dosing.
Effective in a broad range of hypertensive patients.

Side Effects

Ankle swelling (edema)
Headache
Dizziness
Fatigue
Flushing
Nausea
Abdominal discomfort
Orthostatic hypotension
Hyperkalemia
Impaired renal function
Upper respiratory tract infection
Diarrhea

Safety Measures

Alcohol - Concomitant use with alcohol may potentiate hypotensive effects, leading to increased dizziness or fainting. Limit alcohol intake.
Pregnancy - Contraindicated during the second and third trimesters of pregnancy due to the risk of fetal injury or death associated with ARBs.
Breastfeeding - Not recommended during lactation. Consult your healthcare provider to weigh the benefits and risks.
Liver - Exercise caution in patients with mild to moderate hepatic impairment; severe impairment may require dose adjustment or contraindication.
Kidney - Regular monitoring of renal function is advised, especially in patients with pre-existing kidney disease or renovascular hypertension.
Lung - Generally considered safe for individuals with respiratory conditions, as it does not typically exacerbate lung issues.

Disclaimer

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