Combinib 250mg Tablet

About

Combinib 250mg Tablet is a sophisticated targeted therapy medication, classified as a tyrosine kinase inhibitor (TKI). Its primary mechanism involves the selective blockade of specific tyrosine kinases, which are critical enzymes that drive the growth, proliferation, and survival of various cancer cells. By precisely inhibiting these aberrant signaling pathways, Combinib effectively works to impede or halt the progression of certain types of malignancies. This highly targeted approach offers a significant advantage over conventional chemotherapy by focusing its action predominantly on cancerous cells, thereby potentially minimizing damage to healthy tissues and reducing systemic side effects. The prescription of Combinib is typically contingent upon a thorough diagnostic evaluation, including molecular testing, to confirm the presence of specific genetic mutations or biomarkers that indicate the drug's likely efficacy. It represents a crucial advancement in personalized cancer treatment, aiming for improved patient outcomes.

Uses

• Treatment of specific solid tumors with identified genetic mutations.
• Management of certain advanced or metastatic cancers.
• As a maintenance therapy in some cancer types.
• In cases where conventional treatments have been ineffective.

Directions For Use

Take Combinib 250mg Tablet orally as directed by your oncologist, usually once daily with or without food. Do not crush, chew, or break the tablet.

Benefits

• Targeted action against cancer cells.
• Potential for improved progression-free survival.
• May offer an alternative for resistant cancers.
• Oral administration for convenience.
• Generally better tolerability compared to conventional chemotherapy.
• Specific efficacy in mutation-driven cancers.

Side Effects

• Fatigue
• Nausea
• Diarrhea
• Skin rash
• Headache
• Hypertension
• Peripheral edema
• Abdominal pain
• Decreased appetite
• Hair thinning
• Muscle pain
• Elevated liver enzymes

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it may exacerbate liver side effects or interact with the medication.
• Pregnancy - Not recommended during pregnancy due to potential fetal harm; effective contraception is advised for women of childbearing potential.
• Breastfeeding - Breastfeeding is generally not recommended during treatment and for a period after the last dose due to potential drug excretion into breast milk.
• Liver - Use with caution in patients with pre-existing liver impairment; dose adjustments may be necessary, and liver function should be monitored regularly.
• Kidney - Generally safe in mild to moderate renal impairment, but caution and dose adjustments may be required in severe kidney disease.
• Lung - Monitor for new or worsening respiratory symptoms, as interstitial lung disease is a rare but serious side effect.

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