About
Coralan 5 mg contains Ivabradine, a unique bradycardic agent that acts by selectively and specifically inhibiting the If (funny) current in the cardiac sinoatrial node. This action leads to a reduction in heart rate without affecting myocardial contractility, cardiac repolarization, or blood pressure. By slowing the heart rate, Ivabradine decreases myocardial oxygen demand, which is beneficial in conditions where the heart is working too hard.
This medication is primarily indicated for the symptomatic treatment of chronic stable angina pectoris in adults with normal sinus rhythm who have a contraindication or intolerance to beta-blockers, or in combination with beta-blockers in patients inadequately controlled with an optimal beta-blocker dose. It is also used in chronic heart failure with reduced ejection fraction (HFrEF) in patients with normal sinus rhythm and a heart rate of 75 bpm or higher, in combination with standard therapy, including beta-blockers, or when beta-blockers are contraindicated or not tolerated.
Uses
- Symptomatic treatment of chronic stable angina.
- Management of chronic heart failure with reduced ejection fraction.
- Reduces heart rate in patients with normal sinus rhythm.
- Used when beta-blockers are contraindicated or not tolerated.
Directions For Use
Take this medication orally, twice daily, with meals, as prescribed by your doctor.
Benefits
- Reduces heart rate without affecting blood pressure.
- Decreases myocardial oxygen demand.
- Alleviates symptoms of chronic stable angina.
- Improves outcomes in chronic heart failure.
- Offers an alternative for patients intolerant to beta-blockers.
- Enhances exercise tolerance in angina patients.
Side Effects
- Luminous phenomena (phosphenes)
- Bradycardia (slow heart rate)
- Headache
- Dizziness
- Blurred vision
- Atrial fibrillation
- Ventricular extrasystoles
- Nausea
- Constipation
- Dyspnea
- Muscle cramps
- Hypotension
Safety Measures
- Alcohol - No specific interaction with alcohol is known, but moderation is generally advised.
- Pregnancy - Ivabradine is contraindicated during pregnancy due to potential embryofetal toxicity. Women of childbearing potential must use effective contraception.
- Breastfeeding - Ivabradine is contraindicated during breastfeeding as it may be excreted in human milk.
- Liver - Ivabradine is contraindicated in patients with severe hepatic impairment. Use with caution in moderate hepatic impairment.
- Kidney - Use with caution in patients with severe renal impairment (creatinine clearance below 15 mL/min). No dose adjustment is needed for mild to moderate impairment.
- Lung - No specific contraindications for lung conditions. However, caution is advised in patients with severe chronic obstructive pulmonary disease (COPD).
Disclaimer
MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.
Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
| Shipping Cost |
|
| Shop Location | Assam, India |
No comments found for this product. Be the first to comment!