CYBLEX 30 XR 15

About

Gliclazide 30mg XR is an oral hypoglycemic agent belonging to the sulfonylurea class, primarily used in the management of type 2 diabetes mellitus. Its extended-release formulation ensures a sustained therapeutic effect throughout the day, contributing to better glycemic control. The drug works by stimulating the beta cells in the pancreas to release insulin, particularly in the presence of glucose. This mechanism helps to lower blood glucose levels by enhancing glucose uptake and utilization by peripheral tissues and reducing hepatic glucose production.

Gliclazide is often prescribed when diet and exercise alone are insufficient to achieve target blood glucose levels, and it can be used as monotherapy or in combination with other anti-diabetic agents. Its efficacy in reducing HbA1c levels and improving overall glycemic parameters makes it a valuable option in diabetes management, provided patients have residual pancreatic beta-cell function.

Uses

• Management of type 2 diabetes mellitus.
• Lowering high blood sugar levels.
• Improving glycemic control in adults.
• Used when diet and exercise are insufficient.

Directions For Use

Take orally, usually once daily with breakfast. Follow your doctor's prescribed dosage and timing.

Benefits

• Effective in lowering blood glucose.
• Sustained release for once-daily dosing.
• Helps reduce HbA1c levels.
• Improves pancreatic insulin secretion.
• Can be used as monotherapy or combination.
• Contributes to better long-term diabetes management.

Side Effects

• Hypoglycemia (low blood sugar)
• Nausea
• Diarrhea
• Constipation
• Abdominal pain
• Skin rash
• Itching
• Weight gain
• Headache
• Dizziness
• Liver enzyme elevation
• Allergic reactions

Safety Measures

• Alcohol - Alcohol can increase the risk of hypoglycemia when taken with Gliclazide. It should be consumed in moderation or avoided.
• Pregnancy - Gliclazide is generally not recommended during pregnancy. Insulin therapy is usually preferred for glycemic control in pregnant women with diabetes.
• Breastfeeding - It is generally advised to avoid Gliclazide during breastfeeding as it may pass into breast milk and potentially cause hypoglycemia in the infant.
• Liver - Use with caution in patients with liver impairment as it can affect drug metabolism and increase the risk of hypoglycemia. Dose adjustment may be necessary.
• Kidney - Use with caution in patients with kidney impairment. The drug is primarily metabolized by the liver, but severe renal dysfunction can increase accumulation risk.
• Lung - No specific contraindications or major safety concerns related to lung conditions are typically associated with Gliclazide.

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