GLZ MEX TAB 10'S

About

GLZ MEX TAB is a combination medication formulated with Gliclazide and Metformin, indicated for the effective treatment of type 2 diabetes mellitus. Gliclazide, a sulfonylurea, works by stimulating the release of insulin from the pancreatic beta cells, which is crucial for lowering blood glucose levels. Metformin, a biguanide, complements this action by primarily reducing glucose production in the liver, decreasing glucose absorption from the intestines, and enhancing the body's sensitivity to insulin in muscle and fat cells.

This multi-faceted approach ensures a more comprehensive reduction in blood glucose, addressing both insulin secretion and insulin resistance. The combination therapy is particularly valuable for patients whose glycemic control remains inadequate despite diet and exercise, or monotherapy with either Gliclazide or Metformin, helping them achieve and maintain optimal blood sugar targets.

Uses

• Management of type 2 diabetes mellitus.
• Improvement of glycemic control.
• Used as an adjunct to diet and exercise.
• When monotherapy is insufficient.

Directions For Use

Take this medication orally, usually once or twice daily with meals, as prescribed by your doctor.

Benefits

• Effective blood sugar reduction.
• Dual mechanism of action.
• Reduced HbA1c levels.
• Improved insulin sensitivity.
• Reduced hepatic glucose production.
• Comprehensive glycemic control.

Side Effects

• Hypoglycemia (more common than metformin alone)
• Nausea
• Diarrhea
• Vomiting
• Abdominal discomfort
• Headache
• Dizziness
• Metallic taste
• Weight gain (due to gliclazide)
• Skin rash
• Lactic acidosis (rare, serious)
• Vitamin B12 deficiency (with long-term metformin)

Safety Measures

• Alcohol - Avoid excessive alcohol intake as it increases the risk of hypoglycemia and lactic acidosis.
• Pregnancy - Not recommended during pregnancy; insulin is generally preferred for glycemic control.
• Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk; consult a doctor.
• Liver - Use with caution in patients with liver impairment; increased risk of hypoglycemia and lactic acidosis.
• Kidney - Contraindicated in severe renal impairment due to metformin accumulation risk; dose adjustment needed for moderate impairment.
• Lung - Severe respiratory conditions increasing hypoxia risk may increase lactic acidosis risk; use with caution.

Disclaimer

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