D 10% 500ML

About

Dextrose 10% in water (D10W) is a hypertonic intravenous solution containing 10 grams of dextrose per 100 mL. It provides a more substantial caloric source compared to D5W and is used when a greater glucose load is required, such as in moderate hypoglycemia, for nutritional support, or to prevent ketosis during periods of inadequate oral intake. While hypertonic, it is less concentrated than D25W, making it suitable for peripheral vein administration under careful monitoring, though central venous access is preferred for prolonged use. It helps maintain fluid balance and provides essential energy, supporting metabolic needs in various clinical scenarios.

Uses

• Treatment of moderate hypoglycemia.
• Provision of caloric support and energy.
• Prevention and treatment of ketosis.
• Maintenance of fluid and electrolyte balance.

Directions For Use

Administer intravenously as directed by a healthcare professional. Dosage and rate of infusion depend on the patient's age, weight, clinical condition, and glucose requirements.

Benefits

• Provides significant caloric intake.
• Effectively raises blood glucose levels.
• Helps prevent and treat ketosis.
• Supports metabolic needs.
• Contributes to fluid balance.
• Can be used as a vehicle for compatible medications.

Side Effects

• Hyperglycemia.
• Fluid overload/edema.
• Electrolyte imbalances (e.g., hyponatremia, hypokalemia).
• Local pain, irritation, or phlebitis at injection site.
• Extravasation leading to tissue damage.
• Rebound hypoglycemia if infusion stopped abruptly.
• Osmotic diuresis.
• Fever.
• Infection at the injection site.
• Cardiac overload in susceptible patients.
• Allergic reactions (rare).
• Hyperosmolar nonketotic state (less common than D25%).

Safety Measures

• Alcohol - No direct interaction with alcohol, but alcohol can influence blood glucose levels; medical advice should be sought regarding concurrent use.
• Pregnancy - Generally considered safe for use during pregnancy when clinically indicated, but close monitoring of maternal and fetal glucose levels is advised.
• Breastfeeding - Generally considered safe for use during breastfeeding. No known adverse effects on the infant are expected.
• Liver - Use with caution in patients with severe liver impairment, as glucose metabolism may be altered; careful monitoring of blood glucose is necessary.
• Kidney - Use with caution in patients with severe kidney impairment due to the risk of fluid overload and electrolyte disturbances; close monitoring is essential.
• Lung - Use with caution in patients with severe lung conditions (e.g., pulmonary edema) due to the risk of fluid overload exacerbating respiratory distress.

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