DNS 500ML 1X25

About

DNS 500ML refers to Dextrose 5% in Normal Saline (0.9% Sodium Chloride), an intravenous fluid commonly used in clinical practice. This solution combines the benefits of both isotonic saline and a source of free water and calories. The 0.9% sodium chloride component helps to expand the extracellular fluid volume, making it useful for treating dehydration and maintaining electrolyte balance. The 5% dextrose provides approximately 170 calories per 500ml, offering a modest energy source and preventing ketosis, while also being metabolized to provide free water. DNS is frequently administered to patients requiring fluid replacement, electrolyte maintenance, and a small caloric supplement, particularly when oral intake is restricted or insufficient. It is a versatile solution for various medical conditions requiring intravenous hydration and nutritional support.

Uses

• Treatment of dehydration and hypovolemia.
• Maintenance of fluid and electrolyte balance.
• Provision of a modest caloric source and prevention of ketosis.
• As a vehicle for intravenous administration of compatible medications.

Directions For Use

Administer intravenously as directed by a physician. The rate and volume of infusion should be determined by the patient's age, weight, clinical condition, and fluid and electrolyte requirements.

Benefits

• Provides effective hydration and fluid replacement.
• Supplies essential electrolytes (sodium and chloride).
• Offers a source of calories to prevent ketosis.
• Helps restore and maintain fluid balance.
• Compatible with a wide range of intravenous medications.
• Readily available for immediate clinical use.

Side Effects

• Fluid overload, leading to edema or pulmonary congestion.
• Electrolyte imbalances, such as hypernatremia or hypokalemia.
• Hyperglycemia, especially in diabetic patients or with rapid infusion.
• Local irritation, pain, or phlebitis at the injection site.
• Fever or infection due to contamination during administration.
• Allergic reaction to components of the solution.
• Cardiac overload in patients with compromised heart function.
• Hypertension or increased blood pressure.
• Metabolic acidosis (rare, with excessive chloride).
• Hypomagnesemia or hypophosphatemia (with prolonged use).
• Renal impairment exacerbation due to fluid and electrolyte shifts.
• Headache or dizziness.

Safety Measures

• Alcohol - No direct interaction with alcohol. However, caution should be exercised regarding the patient's overall hydration and electrolyte status, especially if alcohol consumption has contributed to dehydration or electrolyte imbalance.
• Pregnancy - Generally considered safe for use during pregnancy for fluid and electrolyte replacement. Close monitoring of fluid balance and serum electrolytes is recommended to prevent complications for both mother and fetus.
• Breastfeeding - Generally considered safe for use during breastfeeding. It is unlikely to pass into breast milk in significant amounts or cause harm to the infant. Monitor the mother's fluid status.
• Liver - Use with caution in patients with severe liver disease, as fluid and electrolyte shifts can be poorly tolerated. Monitor closely for signs of fluid overload or electrolyte imbalance.
• Kidney - Use with extreme caution in patients with renal impairment or kidney disease due to the significant risk of fluid overload, hypernatremia, and other electrolyte disturbances. Close monitoring of renal function, fluid balance, and electrolytes is essential.
• Lung - Use with caution in patients with pulmonary edema, congestive heart failure, or other conditions predisposing to fluid overload, as rapid or excessive infusion can exacerbate respiratory distress. Monitor lung sounds and oxygen saturation.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.