Duplat Depot 22.5mg Injection

About

Duplat Depot 22.5mg Injection is a long-acting formulation designed to continuously release its active pharmaceutical ingredient over an extended period. This medication typically functions as a gonadotropin-releasing hormone (GnRH) analog, which initially stimulates and then downregulates the pituitary gland's production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This sustained suppression leads to a significant reduction in gonadal hormone levels, such as testosterone in men and estrogen in women. It is primarily utilized in the management of hormone-sensitive cancers, like prostate cancer in men and certain types of breast cancer in premenopausal women, as well as other hormone-dependent conditions. The depot formulation ensures consistent therapeutic levels, reducing the frequency of administration.

Uses

• Treatment of advanced prostate cancer.
• Management of hormone-receptor positive breast cancer.
• Therapy for endometriosis.
• Management of uterine fibroids.

Directions For Use

Administer as a subcutaneous or intramuscular injection by a healthcare professional. Follow the prescribed dosing schedule strictly.

Benefits

• Provides sustained hormone suppression.
• Reduces frequency of injections.
• Effective in hormone-sensitive cancers.
• Helps manage endometriosis symptoms.
• Can shrink uterine fibroids.
• Offers a convenient long-term treatment option.

Side Effects

• Hot flashes
• Decreased libido
• Injection site reactions (pain, redness)
• Bone pain (initial flare-up)
• Fatigue
• Headache
• Mood changes
• Weight gain
• Osteoporosis (long-term use)
• Gynecomastia (in men)
• Testicular atrophy (in men)
• Vaginal dryness (in women)

Safety Measures

• Alcohol - No direct interaction with alcohol, but general health recommendations apply. Discuss with your doctor.
• Pregnancy - Contraindicated during pregnancy due to potential harm to the fetus; effective non-hormonal contraception is required.
• Breastfeeding - Not recommended during breastfeeding as the drug may pass into breast milk and affect the infant's hormonal balance.
• Liver - Use with caution in patients with liver impairment; no specific dose adjustments are usually required, but monitor liver function.
• Kidney - No specific dose adjustments are typically needed for patients with renal impairment.
• Lung - No specific contraindications related to lung conditions.

Disclaimer

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