About
Dydrogesterone is a synthetic progestogen that is orally active and structurally similar to natural progesterone. This sustained-release formulation of Dydrogesterone provides a prolonged and steady therapeutic effect, which can improve patient compliance and maintain consistent hormone levels. It selectively acts on the endometrium, inducing a full secretory transformation in an estrogen-primed uterus, which is vital for successful implantation and maintenance of pregnancy. Unlike some other progestogens, dydrogesterone lacks estrogenic, androgenic, anabolic, or corticosteroid activity, making it a highly specific progestogen. It is widely used in conditions of progesterone deficiency, such as threatened or recurrent miscarriage, and in hormone replacement therapy to protect the endometrium from the proliferative effects of estrogen. Its sustained action contributes to better management of chronic gynecological conditions.
Uses
- Treatment of threatened and recurrent miscarriage.
- Management of dysfunctional uterine bleeding.
- Endometriosis.
- Hormone replacement therapy (HRT) to prevent endometrial hyperplasia.
Directions For Use
Take orally with water, preferably at a consistent time each day. Do not crush or chew the tablet.
Benefits
- Sustained release for consistent hormone levels.
- Supports pregnancy by maintaining uterine lining.
- Helps regulate menstrual cycles.
- Reduces risk of endometrial hyperplasia in HRT.
- Highly selective progestogenic action.
- Improved patient compliance due to less frequent dosing.
Side Effects
- Headache
- Nausea
- Abdominal pain
- Breast tenderness
- Dizziness
- Vaginal bleeding/spotting
- Weight gain
- Mood changes
- Skin reactions (rash, itching)
- Fluid retention
- Fatigue
- Migraine
Safety Measures
- Alcohol - No specific interaction with alcohol is known, but moderation is always advised.
- Pregnancy - Used to support pregnancy in specific conditions; consult a doctor before use.
- Breastfeeding - Small amounts may pass into breast milk; generally considered compatible but consult a doctor.
- Liver - Use with caution in patients with liver impairment as it is metabolized by the liver.
- Kidney - Generally considered safe for use in patients with kidney conditions; no dose adjustment typically needed.
- Lung - No specific contraindications or precautions related to lung conditions.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
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