About
Dydrogesterone is a synthetic progestogen that is orally active and structurally similar to natural progesterone. Unlike some other progestogens, dydrogesterone does not possess estrogenic, androgenic, anabolic, or corticosteroid activity, making it a highly selective progestogen. Its primary action is to induce a full secretory endometrium in an estrogen-primed uterus, which is crucial for the establishment and maintenance of pregnancy. It is widely used in conditions where endogenous progesterone is insufficient, such as threatened or recurrent miscarriage, and in hormone replacement therapy to protect the endometrium from the proliferative effects of estrogen. The selective nature of its action minimizes unwanted side effects often associated with less specific progestogens, contributing to its good tolerability profile. Its efficacy in various gynecological conditions makes it a valuable therapeutic option for women's health.
Uses
- Treatment of threatened and recurrent miscarriage.
- Management of dysfunctional uterine bleeding.
- Endometriosis.
- Hormone replacement therapy (HRT) to prevent endometrial hyperplasia.
Directions For Use
Take orally with water, with or without food, as directed by your physician.
Benefits
- Supports pregnancy by maintaining uterine lining.
- Helps regulate menstrual cycles.
- Reduces risk of endometrial hyperplasia in HRT.
- Highly selective progestogenic action.
- Good tolerability profile.
- Effective in managing various gynecological conditions.
Side Effects
- Headache
- Nausea
- Abdominal pain
- Breast tenderness
- Dizziness
- Vaginal bleeding/spotting
- Weight gain
- Mood changes
- Skin reactions (rash, itching)
- Fluid retention
- Fatigue
- Migraine
Safety Measures
- Alcohol - No specific interaction with alcohol is known, but moderation is always advised.
- Pregnancy - Used to support pregnancy in specific conditions; consult a doctor before use.
- Breastfeeding - Small amounts may pass into breast milk; generally considered compatible but consult a doctor.
- Liver - Use with caution in patients with liver impairment as it is metabolized by the liver.
- Kidney - Generally considered safe for use in patients with kidney conditions; no dose adjustment typically needed.
- Lung - No specific contraindications or precautions related to lung conditions.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
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