About
Eurolide 1mg Injection contains Leuprolide, a synthetic analogue of gonadotropin-releasing hormone (GnRH). Its mechanism of action involves an initial transient stimulation of GnRH receptors in the pituitary gland, followed by a sustained desensitization and downregulation of these receptors. This leads to a significant and prolonged suppression of pituitary gonadotropin release, specifically luteinizing hormone (LH) and follicle-stimulating hormone (FSH). As a result, the production of sex hormones, such as testosterone in males and estrogen in females, is profoundly reduced, creating a state of chemical castration or menopause, depending on the patient's sex.
This medication is primarily used in the management of various hormone-dependent conditions. In men, it is indicated for the palliative treatment of advanced prostate cancer, where it helps to reduce testosterone levels and slow disease progression. In women, it is utilized for the management of endometriosis and uterine fibroids, by inducing a hypoestrogenic state that alleviates symptoms and reduces lesion size. It is also an effective treatment for central precocious puberty in children, by suppressing premature sexual development. The daily injection regimen allows for precise control over hormonal suppression.
Uses
- Palliative treatment of advanced prostate cancer.
- Management of endometriosis.
- Treatment of uterine fibroids.
- Management of central precocious puberty.
Directions For Use
Eurolide 1mg Injection is administered subcutaneously by a healthcare professional, typically once daily. Follow your doctor's instructions regarding the exact dosage and administration schedule.
Benefits
- Suppresses sex hormone production effectively.
- Helps manage advanced prostate cancer.
- Reduces symptoms of endometriosis.
- Shrinks uterine fibroids.
- Controls central precocious puberty.
- Provides precise daily hormonal control.
Side Effects
- Hot flashes
- Sweating
- Fatigue
- Headache
- Nausea
- Injection site reactions
- Bone pain (initial flare)
- Decreased libido
- Erectile dysfunction (men)
- Vaginal dryness (women)
- Mood changes
- Muscle pain
Safety Measures
- Alcohol - No specific contraindication with alcohol, but general moderation is advisable.
- Pregnancy - Eurolide is contraindicated in pregnancy due to the risk of fetal harm. Effective non-hormonal contraception should be used.
- Breastfeeding - Not recommended during breastfeeding as it may interfere with lactation and potentially harm the infant.
- Liver - Use with caution in patients with liver impairment; however, significant dose adjustment is generally not required.
- Kidney - No specific dose adjustment is typically needed for patients with renal impairment.
- Lung - No specific lung-related safety concerns are commonly associated with Leuprolide.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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