About

Ferric Carboxymaltose (FCM) is an intravenous iron preparation used for the rapid and effective treatment of iron deficiency anemia when oral iron is ineffective or cannot be tolerated. It delivers iron directly to the reticuloendothelial system, where it is released and incorporated into hemoglobin, myoglobin, and other iron-containing enzymes. This formulation allows for the administration of a high dose of iron in a single or few infusions, quickly replenishing iron stores and increasing hemoglobin levels.

It is particularly beneficial for patients with chronic kidney disease, inflammatory bowel disease, or those who have undergone bariatric surgery, where oral iron absorption is compromised. The rapid repletion helps alleviate symptoms such as fatigue, weakness, and shortness of breath, significantly improving the patient's quality of life.

Uses

Treatment of iron deficiency anemia.
When oral iron is ineffective or poorly tolerated.
In patients with chronic kidney disease not on dialysis.
For iron deficiency in inflammatory bowel disease.

Directions For Use

Administer intravenously as a slow infusion by a healthcare professional. Dosage is determined by the patient's iron deficit and body weight.

Benefits

Rapid replenishment of iron stores.
Quick increase in hemoglobin levels.
Effective for severe iron deficiency.
Bypasses gastrointestinal absorption issues.
Reduces symptoms of anemia quickly.
Allows for high-dose administration in fewer visits.

Side Effects

Nausea
Headache
Dizziness
Injection site reactions
Hypophosphatemia
Hypertension
Flushing
Rash
Abdominal pain
Diarrhea
Constipation
Hypersensitivity reactions (rare but serious)

Safety Measures

Alcohol - No direct interaction, but excessive alcohol can impair iron absorption or exacerbate liver conditions.
Pregnancy - Use only if clearly needed, especially in the first trimester. Consult a doctor.
Breastfeeding - Small amounts may pass into breast milk; generally considered safe, but consult a healthcare provider.
Liver - Use with caution in patients with liver impairment; iron overload can be a concern.
Kidney - Often used in chronic kidney disease, but monitor for fluid overload and iron parameters.
Lung - No specific contraindications, but monitor for hypersensitivity reactions which can affect respiratory function.

Disclaimer

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