About
GABANICHE NT TAB is a synergistic combination medication, typically formulated with Gabapentin and Nortriptyline, specifically engineered to provide comprehensive and enhanced relief for various forms of neuropathic pain and associated mood disturbances. Gabapentin, an anticonvulsant, exerts its analgesic effects by modulating voltage-gated calcium channels and influencing the release of excitatory neurotransmitters, thereby dampening aberrant nerve pain signals. Nortriptyline, a tricyclic antidepressant, complements this action by inhibiting the reuptake of norepinephrine and serotonin, which are crucial neurotransmitters involved in descending pain modulation pathways and mood regulation. This dual-action approach targets multiple pathophysiological mechanisms underlying chronic pain, offering superior symptom control compared to monotherapy. It is particularly beneficial for challenging conditions such as diabetic neuropathy, postherpetic neuralgia, and other complex chronic pain syndromes, often improving sleep quality and reducing the emotional burden of pain.
Uses
- Management of neuropathic pain (e.g., diabetic neuropathy).
- Treatment of postherpetic neuralgia.
- Adjunctive therapy for certain chronic pain syndromes.
- May help with associated sleep disturbances.
Directions For Use
Take orally as prescribed by your doctor, usually in divided doses. Do not stop abruptly.
Benefits
- Provides comprehensive relief for neuropathic pain.
- Targets multiple pain pathways for enhanced efficacy.
- Can improve sleep quality in pain patients.
- May reduce anxiety associated with chronic pain.
- Offers a synergistic effect compared to monotherapy.
- Reduces the need for higher doses of individual components.
Side Effects
- Drowsiness/Sedation
- Dizziness
- Dry mouth
- Constipation
- Blurred vision
- Weight gain
- Peripheral edema
- Orthostatic hypotension
- Nausea
- Confusion
- Urinary retention
- Tremor
Safety Measures
- Alcohol - Avoid alcohol as it can significantly enhance central nervous system depression, drowsiness, and dizziness.
- Pregnancy - Use with caution; consult a doctor. Both components have potential risks during pregnancy, and benefits must outweigh risks.
- Breastfeeding - Not recommended as both components pass into breast milk and may cause adverse effects in the infant. Consult a physician.
- Liver - Use with caution in patients with liver impairment; dose adjustment may be necessary for both components due to hepatic metabolism.
- Kidney - Use with caution in patients with kidney impairment, especially for Gabapentin, which is renally excreted; dose adjustment is often necessary.
- Lung - Use with caution in patients with severe respiratory conditions due to potential for respiratory depression, especially with Nortriptyline.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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| Shop Location | Assam, India |
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