MEGANEURON PG CAP 10.S

About

Pregabalin is an alpha-2-delta ligand, classified as an anticonvulsant and neuropathic pain agent. Its primary mechanism of action involves binding with high affinity to the alpha-2-delta subunit of voltage-gated calcium channels located in the central nervous system. This binding modulates the influx of calcium into presynaptic neurons, which in turn reduces the release of several excitatory neurotransmitters, including glutamate, norepinephrine, and substance P. By dampening this excessive neuronal activity, Pregabalin effectively reduces the transmission of pain signals, calms overactive nerve impulses, and exerts anxiolytic effects. It is widely indicated for the management of various forms of neuropathic pain, such as diabetic neuropathy and post-herpetic neuralgia, as well as for fibromyalgia, generalized anxiety disorder, and as an adjunctive therapy for partial-onset seizures. Its broad spectrum of action makes it a valuable agent in chronic pain and neurological conditions.

Uses

• Treatment of neuropathic pain.
• Management of fibromyalgia.
• Adjunctive therapy for partial-onset seizures.
• Treatment of generalized anxiety disorder.

Directions For Use

Take the capsule orally, usually two or three times daily, with or without food, as directed by your physician.

Benefits

• Effective relief from nerve pain.
• Reduces seizure frequency.
• Alleviates anxiety symptoms.
• Improves sleep quality.
• Reduces pain associated with fibromyalgia.
• Well-tolerated by many patients.

Side Effects

• Dizziness
• Somnolence (drowsiness)
• Peripheral edema (swelling)
• Weight gain
• Blurred vision
• Dry mouth
• Difficulty concentrating
• Ataxia (impaired coordination)
• Headache
• Nausea
• Fatigue
• Tremor

Safety Measures

• Alcohol - Avoid alcohol as it can intensify central nervous system depression and side effects like dizziness and drowsiness.
• Pregnancy - Consult your doctor; Pregabalin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
• Breastfeeding - Pregabalin is excreted in breast milk; discuss with your doctor before breastfeeding.
• Liver - No specific dose adjustment is typically required for mild to moderate liver impairment.
• Kidney - Dose adjustment is necessary for patients with impaired kidney function due to renal excretion.
• Lung - Use with caution in patients with respiratory compromise, as it can cause respiratory depression, especially with concomitant CNS depressants.

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