About

Zolfresh 5mg and 10mg tablets contain Zolpidem, a non-benzodiazepine hypnotic agent specifically designed for the short-term treatment of insomnia. Its mechanism of action involves selectively binding to the omega-1 subtype of the gamma-aminobutyric acid (GABA) A receptor complex in the brain. This selective binding enhances the inhibitory effects of GABA, the brain's primary inhibitory neurotransmitter, leading to central nervous system depression. The result is a rapid onset of sedative and hypnotic effects, which helps patients fall asleep quickly and maintain sleep. Zolpidem is particularly effective for individuals experiencing difficulties with sleep initiation. Due to its relatively short half-life, it helps to minimize residual daytime sedation, making it a preferred choice for many. However, it is crucial to use this medication strictly as prescribed by a healthcare professional to mitigate the risks of dependence, tolerance, and potential withdrawal symptoms upon discontinuation.

Uses

Short-term treatment of insomnia.
Facilitating sleep onset.
Improving sleep duration in some cases.
Management of transient or chronic insomnia.

Directions For Use

Take one tablet orally immediately before bedtime, on an empty stomach. Do not take with or immediately after a meal.

Benefits

Rapid onset of sleep.
Helps to fall asleep faster.
Reduces nighttime awakenings.
Improves overall sleep quality.
Relatively short duration of action.
Minimizes next-day grogginess compared to some older hypnotics.

Side Effects

Drowsiness
Dizziness
Headache
Nausea
Diarrhea
Dry mouth
Memory impairment (amnesia)
Hallucinations
Sleepwalking or other complex sleep behaviors
Paradoxical excitation
Dependence and withdrawal symptoms
Allergic reactions

Safety Measures

Alcohol - Avoid alcohol completely as it significantly enhances the sedative effects and increases the risk of serious side effects.
Pregnancy - Not recommended during pregnancy, especially in the third trimester, due to potential fetal harm. Consult a doctor.
Breastfeeding - Excreted into breast milk; not recommended during breastfeeding due to potential infant sedation.
Liver - Use with caution in patients with liver impairment; dosage reduction is often necessary.
Kidney - Use with caution in patients with kidney impairment; dosage adjustments may be needed.
Lung - Use with caution in patients with respiratory depression or sleep apnea, as it can worsen breathing difficulties.

Disclaimer

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