About

Valproic acid, the active ingredient in VALANCE OD, is an anticonvulsant medication primarily utilized in the management of epilepsy and bipolar disorder. Its mechanism of action involves increasing the levels of gamma-aminobutyric acid (GABA) in the brain, a neurotransmitter that inhibits neuronal excitability, thereby reducing the frequency and severity of seizures. Furthermore, it exhibits mood-stabilizing properties, making it effective in controlling manic or mixed episodes associated with bipolar disorder. The "OD" designation typically signifies an extended-release formulation, designed to provide a more consistent drug concentration over a prolonged period, which can enhance patient adherence and reduce fluctuations in therapeutic effect.

This medication plays a vital role in the long-term treatment of these neurological and psychiatric conditions, aiming to restore balance in brain activity and improve the patient's overall quality of life. Due to its pharmacokinetic profile and potential for adverse effects, regular monitoring of drug levels, liver function, and platelet counts is often necessary to ensure optimal therapeutic outcomes and patient safety.

Uses

Treatment of various seizure types (e.g., absence, complex partial, generalized tonic-clonic).
Management of manic or mixed episodes associated with bipolar disorder.
Prophylaxis of migraine headaches.
Adjunctive therapy in certain psychiatric conditions.

Directions For Use

Take this medication orally, usually once daily, with or without food, as directed by your doctor. Do not crush or chew extended-release tablets.

Benefits

Effective in controlling a broad spectrum of seizure types.
Provides mood stabilization for bipolar disorder.
Reduces frequency and severity of migraine attacks.
Available in extended-release formulation for convenience.
Helps improve overall neurological and mental well-being.
Well-established efficacy in its indications.

Side Effects

Nausea, vomiting, diarrhea
Abdominal pain
Drowsiness, dizziness
Tremor
Hair loss
Weight gain
Headache
Blurred vision
Thrombocytopenia (low platelet count)
Liver dysfunction (rare but serious)
Pancreatitis (rare but serious)
Sedation

Safety Measures

Alcohol - Avoid alcohol consumption as it can increase drowsiness and dizziness, and may exacerbate liver toxicity associated with valproic acid.
Pregnancy - Valproic acid is associated with a significant risk of birth defects (e.g., neural tube defects) and developmental problems. Use only if benefits outweigh risks, and consider alternative treatments.
Breastfeeding - Valproic acid passes into breast milk. Consult a doctor; monitoring the infant for sedation or feeding difficulties may be advised.
Liver - Use with extreme caution in patients with pre-existing liver disease or dysfunction. Regular liver function tests are essential due to the risk of hepatotoxicity.
Kidney - Generally, no dose adjustment is needed for mild to moderate renal impairment, but caution is advised in severe cases.
Lung - No specific contraindications or significant concerns related to lung conditions are typically noted for valproic acid.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.

Shipping & Location