GAMMAREN 5GM 100 ML INJ. VIAL

About

Gammaren 5GM 100 ML Injection VIAL contains Intravenous Immunoglobulin (IVIG), a sterile solution of concentrated antibodies (immunoglobulins) derived from human plasma. IVIG provides passive immunity by supplying a broad spectrum of IgG antibodies, which are crucial for fighting infections and modulating the immune system. It is used to treat a wide range of primary and secondary immunodeficiency states, where the body's ability to produce its own antibodies is impaired, as well as various autoimmune and inflammatory disorders.

The therapeutic effects of IVIG include neutralizing pathogenic antibodies, blocking Fc receptors, suppressing autoantibody production, and modulating cytokine production. Its diverse mechanisms of action make it a versatile treatment for conditions such as idiopathic thrombocytopenic purpura (ITP), Kawasaki disease, and certain neurological disorders. Administration is typically via slow intravenous infusion, with careful monitoring for infusion-related reactions.

Uses

• Primary immunodeficiency syndromes
• Idiopathic thrombocytopenic purpura (ITP)
• Kawasaki disease
• Chronic inflammatory demyelinating polyneuropathy (CIDP)

Directions For Use

Administered intravenously by a healthcare professional. The infusion rate and dosage are determined by the physician based on the patient's condition.

Benefits

• Replaces missing antibodies in immunodeficiency
• Modulates the immune system in autoimmune diseases
• Prevents serious infections in immunocompromised patients
• Treats various inflammatory and neurological conditions
• Broad therapeutic applications
• Improves patient outcomes in specific disorders

Side Effects

• Headache
• Fever and chills
• Nausea and vomiting
• Fatigue
• Rash
• Back pain
• Joint pain
• Flushing
• Hypotension or Hypertension
• Aseptic meningitis (rare)
• Renal dysfunction (rare)
• Thrombotic events (rare)

Safety Measures

• Alcohol - No specific interaction with alcohol is known; generally not contraindicated.
• Pregnancy - Use if clearly indicated and benefits outweigh risks; generally considered safe, but consult a physician.
• Breastfeeding - Considered safe during breastfeeding as antibodies are naturally present in breast milk and are beneficial for the infant.
• Liver - Use with caution in patients with pre-existing liver disease; monitor liver function during treatment.
• Kidney - Use with caution in patients with renal impairment or risk factors for acute renal failure; ensure adequate hydration and slow infusion rate.
• Lung - Use with caution in patients with pulmonary conditions or risk factors for fluid overload; monitor respiratory status.

Disclaimer

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