HETGLOBY 5% I.P. 5GM 100ML VIAL

About

HETGLOBY 5% I.P. is a sterile intravenous infusion solution that contains Hydroxyethyl Starch (HES) 5% as the active ingredient. It is commonly used as a plasma volume expander in the management of hypovolemia (low blood volume), which may result from conditions such as blood loss, dehydration, or surgery.

This solution helps restore and maintain blood pressure and volume by increasing the volume of fluid in the blood vessels. It is typically administered in hospital settings under the supervision of healthcare professionals.

HETGLOBY 5% is supplied in a 100 ml vial, with each vial containing 5 grams of hydroxyethyl starch. The dosage and duration of treatment depend on the patient's condition, fluid status, and clinical response.

This medication should only be used under medical guidance due to the potential risk of adverse effects, particularly in patients with kidney dysfunction, heart failure, or coagulation disorders. Regular monitoring of kidney function, coagulation parameters, and fluid balance is advised during treatment.

Uses

• Treatment of Hypovolemia

  • Used to treat or prevent low blood volume (hypovolemia) due to blood loss, dehydration, or surgical procedures.

• Supportive Care in Shock

  • Administered in cases of shock caused by trauma, burns, or sepsis to help maintain blood circulation and stabilize blood pressure.

• During Major Surgeries

  • Used during or after major surgeries to maintain adequate blood volume and tissue perfusion, especially when there is significant blood loss.

• Acute Blood Loss

  • Acts as a temporary substitute for blood by expanding plasma volume until blood transfusion is available or necessary.

Directions for use

This medicine will be administered by your doctor or nurse. Please do not attempt to self-administer it.


Side effects

• Nausea or vomiting
• Mild fever
• Itching (pruritus)
• Headache
• Redness or swelling at the injection site
• Allergic reactions – rash, itching, swelling, dizziness, difficulty breathing (anaphylaxis)
• Kidney impairment or failure – reduced urine output, swelling in legs, fatigue
• Coagulation problems – increased risk of bleeding or bruising
• Liver dysfunction – elevated liver enzymes in blood tests
• Fluid overload or heart failure – especially in patients with pre-existing heart or kidney conditions
• Allergic reactions – rash, itching, swelling, dizziness, difficulty breathing (anaphylaxis)
• Kidney impairment or failure – reduced urine output, swelling in legs, fatigue
• Coagulation problems – increased risk of bleeding or bruising
• Liver dysfunction – elevated liver enzymes in blood tests
• Fluid overload or heart failure – especially in patients with pre-existing heart or kidney conditions

Safety Measures

Alcohol - There is limited data on alcohol interaction. Avoid alcohol during treatment, especially if being treated for shock or critical illness. Please consult your doctor for personalized advice.
Pregnancy - Safety in pregnancy is not well established. It should only be used if clearly needed and prescribed by a doctor.
Breastfeeding - It is unknown if Hydroxyethyl Starch passes into breast milk. Use only if the potential benefit justifies the potential risk to the infant.
Liver - HES may affect liver function. Liver parameters should be monitored during treatment, especially in patients with existing liver disease.
Kidney - HETGLOBY 5% can increase the risk of acute kidney injury, especially in critically ill or septic patients. It is not recommended in patients with severe renal impairment or those on dialysis. Kidney function must be closely monitored.

Disclaimer

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