About

Pegcyte 6mg Injection contains Pegfilgrastim as its active ingredient and belongs to the class of granulocyte colony-stimulating factors (G-CSF). Approved by the FDA, this medication is used to reduce the risk and duration of febrile neutropenia—a condition involving fever or infection due to low white blood cell (WBC) counts—in patients undergoing bone marrow-suppressing chemotherapy. It is also indicated to improve survival rates in individuals exposed to radiation therapy, which can severely damage the bone marrow. Pegfilgrastim works by stimulating the production and function of blood-forming cells in the bone marrow.

Pegfilgrastim is a biotechnologically engineered protein produced in E. coli and belongs to the cytokine protein family. It mimics the natural granulocyte-colony stimulating factor (G-CSF) produced in the human body. Since WBCs play a crucial role in fighting infections, a drop in their levels—especially during chemotherapy—can leave the body vulnerable to serious infections. This medication helps boost WBC production to lower that risk.

Before starting Pegcyte 6mg Injection, inform your doctor if you have a history of liver or kidney disease, infections, fever, heart conditions, or a family history of kidney disorders. Do not use this medication if you are allergic to Pegfilgrastim, Filgrastim, or any of its components. Notify your healthcare provider immediately if you experience left upper abdominal pain, shoulder pain, or breathing difficulties, as these may be signs of serious side effects. The most commonly reported side effects include bone pain, as well as pain in the arms or legs.

Uses

Decrease the chance of infection caused by low levels of white blood cells in patients with certain types of cancer (non-myeloid) receiving bonemarrow suppressing anti-cancer drugs.
To increase the survival rate in patients receiving radiation therapy that suppresses bone marrow activity.

Directions for use

This medicine will be administered by your doctor or nurse. Please do not attempt to self-administer it.

Side effects

Pain in the bones, joints and muscles
Pain at the site of Injection
Itchiness and skin rash
Nausea
Headaches
Dizziness and tiredness
Inflammation of Aorta
Capillary leak syndrome (plasma leaks out of tiny blood vessels)
Hypersensitivity reactions
Changes in urine color
Swelling in hands, feet, face, and abdomen
Difficulty in breathing
Sickle cell anemia

Safety Measures

Alcohol - Avoid consuming alcohol during treatment with Pegcyte 6mg Injection. Alcohol may interfere with the medication’s effects. Consult your doctor for further guidance.
Pregnancy - Pegcyte 6mg Injection should not be used during pregnancy, as it may cause harm or birth defects to the unborn baby. Inform your doctor if you are pregnant or planning to become pregnant during treatment.
Breastfeeding - Breastfeeding is not recommended while undergoing treatment with Pegcyte 6mg Injection, as it may harm the baby. Please consult your doctor before breastfeeding.
Liver - It is unclear if Pegcyte 6mg Injection is safe for patients with liver conditions. Inform your healthcare provider if you have any liver problems before starting treatment.
Kidney - If you have kidney disease or any kidney-related issues, inform your healthcare provider before starting Pegcyte 6mg Injection, as close monitoring may be necessary.

Disclaimer

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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

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