GLUGRIP 0.5 10S

About

GLUGRIP 0.5 contains Glimepiride 0.5mg, an oral sulfonylurea antidiabetic agent used to effectively lower blood glucose levels in patients diagnosed with type 2 diabetes mellitus. Its principal mode of action involves stimulating the pancreatic beta cells to augment insulin secretion, particularly when glucose levels are elevated. Furthermore, glimepiride may contribute to better glycemic control by enhancing peripheral insulin sensitivity and diminishing hepatic glucose production. This lower dosage is often preferred for initiating therapy in newly diagnosed patients, in individuals who are particularly sensitive to antidiabetic medications, or when a milder glucose-lowering effect is desired to minimize the risk of hypoglycemia. It serves as an important adjunct to diet and exercise, forming a cornerstone of treatment when lifestyle modifications alone are insufficient to achieve target blood glucose levels.

Uses

• Management of type 2 diabetes mellitus.
• Lowering blood glucose levels.
• Stimulating insulin release from the pancreas.
• Used as an adjunct to diet and exercise.

Directions For Use

Take orally once daily with the first main meal of the day, as directed by your physician.

Benefits

• Effective in lowering blood glucose.
• Lower dose for sensitive patients.
• Improves pancreatic insulin secretion.
• May enhance peripheral insulin sensitivity.
• Helps achieve glycemic targets.
• Well-established treatment option.

Side Effects

• Hypoglycemia (low blood sugar)
• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Weight gain
• Allergic skin reactions (rash, pruritus)
• Photosensitivity
• Liver enzyme elevation
• Leukopenia/Thrombocytopenia (rare)

Safety Measures

• Alcohol - Avoid alcohol due to increased risk of hypoglycemia and disulfiram-like reactions.
• Pregnancy - Not recommended; insulin is generally preferred for gestational diabetes.
• Breastfeeding - Not recommended; glimepiride may pass into breast milk and cause infant hypoglycemia.
• Liver - Use with caution; dose adjustment may be needed in mild to moderate impairment, contraindicated in severe.
• Kidney - Use with caution; dose adjustment is necessary in renal impairment to avoid hypoglycemia.
• Lung - No specific contraindications; manage diabetes carefully in patients with lung conditions.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.