GLUGRIP 2 10S

About

GLUGRIP 2 contains Glimepiride 2mg, an oral sulfonylurea antidiabetic agent specifically indicated for the management of type 2 diabetes mellitus. Its primary mechanism of action involves stimulating the beta cells within the pancreatic islets to increase the secretion of insulin, particularly in response to elevated glucose levels. Beyond its direct effect on insulin release, glimepiride also contributes to improved glycemic control by potentially enhancing peripheral insulin sensitivity and reducing the liver's production of glucose. This medication is typically prescribed as an essential adjunct to dietary modifications and regular exercise, especially when lifestyle interventions alone prove insufficient in achieving adequate blood glucose regulation. The convenience of its once-daily dosing regimen, usually taken with the first main meal, supports patient adherence and simplifies the long-term management of chronic diabetes.

Uses

• Management of type 2 diabetes mellitus.
• Lowering blood glucose levels.
• Stimulating insulin release from the pancreas.
• Used as an adjunct to diet and exercise.

Directions For Use

Take orally once daily with the first main meal of the day, as directed by your physician.

Benefits

• Effective in lowering blood glucose.
• Once-daily dosing for convenience.
• Improves pancreatic insulin secretion.
• May enhance peripheral insulin sensitivity.
• Helps achieve glycemic targets.
• Well-established treatment option.

Side Effects

• Hypoglycemia (low blood sugar)
• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Weight gain
• Allergic skin reactions (rash, pruritus)
• Photosensitivity
• Liver enzyme elevation
• Leukopenia/Thrombocytopenia (rare)

Safety Measures

• Alcohol - Avoid alcohol due to increased risk of hypoglycemia and disulfiram-like reactions.
• Pregnancy - Not recommended; insulin is generally preferred for gestational diabetes.
• Breastfeeding - Not recommended; glimepiride may pass into breast milk and cause infant hypoglycemia.
• Liver - Use with caution; dose adjustment may be needed in mild to moderate impairment, contraindicated in severe.
• Kidney - Use with caution; dose adjustment is necessary in renal impairment to avoid hypoglycemia.
• Lung - No specific contraindications; manage diabetes carefully in patients with lung conditions.

Disclaimer

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