ITRATUF SB 130 10S

About

ITRATUF contains Itraconazole, a broad-spectrum triazole antifungal agent used to treat various systemic and superficial fungal infections. It works by inhibiting the fungal cytochrome P450-dependent enzyme lanosterol 14α-demethylase, which is essential for ergosterol synthesis, a vital component of the fungal cell membrane. This disruption leads to increased cellular permeability and ultimately fungal cell death. Itraconazole is effective against dermatophytes, yeasts (like Candida), and various dimorphic fungi. It is commonly prescribed for onychomycosis, systemic candidiasis, aspergillosis, histoplasmosis, and blastomycosis. The "SB" formulation (e.g., ITRATUF SB 130) often indicates a specialized delivery system designed to enhance absorption and bioavailability, improving therapeutic outcomes.

Uses

• Treatment of fungal nail infections (onychomycosis).
• Management of systemic fungal infections (e.g., aspergillosis).
• Treatment of oral and vaginal candidiasis.
• Eradication of dermatophyte infections.

Directions For Use

Take capsules orally immediately after a full meal to ensure optimal absorption. Follow your doctor's prescribed dosage and duration strictly.

Benefits

• Effective against a wide range of fungal pathogens.
• Treats both superficial and systemic infections.
• Available in oral form for convenient administration.
• Can be used for pulse dosing regimens.
• Penetrates well into various tissues.
• Helps clear persistent fungal conditions.

Side Effects

• Nausea
• Abdominal pain
• Diarrhea
• Headache
• Dizziness
• Rash
• Liver enzyme elevation
• Fatigue
• Edema
• Hypertension
• Hypokalemia
• Congestive heart failure (rare, serious)

Safety Measures

• Alcohol - Avoid alcohol consumption as it can increase the risk of liver damage and exacerbate side effects; use with extreme caution.
• Pregnancy - Contraindicated during pregnancy due to potential for teratogenicity; effective contraception is required during treatment and for two months after.
• Breastfeeding - Not recommended during breastfeeding as it passes into breast milk and may harm the infant; an alternative should be considered.
• Liver - Contraindicated in patients with a history of liver disease or elevated liver enzymes; monitor liver function closely during treatment.
• Kidney - Use with caution in patients with kidney impairment; dosage adjustment may be necessary, and renal function should be monitored.
• Lung - Use with caution in patients with a history of heart failure or pulmonary disease, as it can exacerbate fluid retention and dyspnea.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.