Lupride 1mg Injection

About

Lupride 1mg Injection contains leuprolide acetate, a synthetic nonapeptide analog of naturally occurring gonadotropin-releasing hormone (GnRH). It functions by initially stimulating the GnRH receptors in the pituitary gland, leading to a transient surge in gonadotropin release. However, with continuous administration, it causes a desensitization and downregulation of these receptors, resulting in a profound and sustained suppression of pituitary gonadotropin secretion, specifically luteinizing hormone (LH) and follicle-stimulating hormone (FSH).

This sustained suppression of LH and FSH subsequently leads to a significant reduction in the production of gonadal steroids, such as testosterone in males and estrogen in females. This hormonal deprivation is therapeutically beneficial in managing various hormone-dependent conditions, including advanced prostate cancer, endometriosis, and uterine fibroids. The daily administration of the 1mg formulation allows for precise control over hormonal suppression, often used in specific protocols or for initial dose titration.

Uses

• Treatment of advanced prostate cancer
• Management of endometriosis
• Pre-surgical treatment of uterine fibroids
• Treatment of central precocious puberty

Directions For Use

Administer as a daily subcutaneous injection, typically in the abdominal wall, thigh, or upper arm. Follow your doctor's instructions precisely regarding dosage and injection technique.

Benefits

• Effectively reduces sex hormone levels
• Helps control prostate cancer progression
• Alleviates pain and symptoms of endometriosis
• Reduces the size of uterine fibroids
• Delays premature puberty in children
• Allows for precise daily dose adjustment

Side Effects

• Hot flashes
• Injection site reactions (redness, pain)
• Decreased libido
• Bone mineral density reduction
• Mood disturbances
• Headache
• Nausea
• Fatigue
• Muscle aches
• Weight fluctuations
• Vaginal dryness
• Breast tenderness

Safety Measures

• Alcohol - No specific contraindication with alcohol, but moderation is generally recommended. Discuss with your healthcare provider.
• Pregnancy - Contraindicated during pregnancy due to the risk of adverse effects on fetal development. Ensure effective contraception.
• Breastfeeding - Not advised for use while breastfeeding as it may pass into breast milk and potentially harm the infant.
• Liver - Use with caution in patients with impaired liver function. Regular monitoring of liver enzymes may be necessary.
• Kidney - Generally safe for use in patients with kidney disease; dose adjustments are typically not required.
• Lung - No specific precautions for patients with lung conditions. Use as directed by your physician.

Disclaimer

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