About
This combination therapy synergistically addresses neuropathic pain by integrating the distinct pharmacological actions of Pregabalin and Methylcobalamin. Pregabalin, an alpha-2-delta ligand, functions by binding to specific subunits of voltage-gated calcium channels in the central nervous system. This interaction reduces the release of excitatory neurotransmitters, such as glutamate and substance P, thereby effectively dampening the overactive nerve signals responsible for chronic pain. Concurrently, Methylcobalamin, an active form of Vitamin B12, is crucial for maintaining nerve health and promoting nerve regeneration. It plays a vital role in the synthesis of myelin, the protective sheath around nerve fibers, and supports the metabolic processes essential for neuronal repair. By combining these agents, the medication not only provides symptomatic relief from burning, tingling, and shooting pains but also supports the underlying physiological processes of nerve repair and maintenance, offering a more holistic approach to managing complex neuropathic conditions.
Uses
- Management of chronic neuropathic pain.
- Treatment of diabetic neuropathy.
- Relief from post-herpetic neuralgia.
- Support for nerve regeneration and health.
Directions For Use
Take this medication orally, usually once daily, preferably at bedtime, or as advised by your healthcare provider.
Benefits
- Dual action for nerve pain relief.
- Promotes nerve repair and regeneration.
- Reduces burning, tingling, and numbness.
- Improves overall nerve function.
- Enhances quality of life for chronic pain sufferers.
- Convenient once-daily dosing.
Side Effects
- Dizziness
- Drowsiness
- Peripheral edema
- Weight gain
- Blurred vision
- Dry mouth
- Headache
- Nausea
- Fatigue
- Difficulty concentrating
- Ataxia
- Constipation
Safety Measures
- Alcohol - Avoid alcohol as it can significantly increase central nervous system depression and adverse effects.
- Pregnancy - Consult your doctor; use only if the potential benefit justifies the potential risk to the fetus.
- Breastfeeding - Pregabalin is excreted in breast milk; discuss with your doctor before breastfeeding.
- Liver - No specific dose adjustment for Pregabalin in mild to moderate liver impairment; Methylcobalamin is generally safe.
- Kidney - Dose adjustment for Pregabalin is necessary in patients with impaired kidney function.
- Lung - Use with caution in patients with respiratory compromise, especially with concomitant CNS depressants, due to potential for respiratory depression.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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| Shop Location | Assam, India |
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