MET XL T25/40 20

About

Met XL T25/40 is a fixed-dose combination medication indicated for the treatment of essential hypertension. It typically combines Metoprolol XL (a beta-blocker) at a dose of 25mg with Telmisartan (an angiotensin receptor blocker, ARB) at a dose of 40mg. Metoprolol XL works by selectively blocking beta-1 adrenergic receptors, leading to a reduction in heart rate and cardiac output, thereby lowering blood pressure. Telmisartan acts by blocking the angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II, which also results in blood pressure reduction. This synergistic action provides a comprehensive approach to blood pressure control, offering sustained efficacy and reducing the risk of cardiovascular complications in patients whose blood pressure is not adequately controlled by monotherapy.

Uses

• Treatment of essential hypertension
• Management of high blood pressure not controlled by a single agent
• Prevention of cardiovascular events in hypertensive patients
• Improvement of cardiac function and vascular health

Directions For Use

Take one tablet orally once daily, preferably at the same time each day. Swallow the tablet whole with water, with or without food, as directed by your physician.

Benefits

• Effective and sustained blood pressure control
• Reduces the risk of heart attack and stroke
• Combines two complementary mechanisms of action
• Provides 24-hour blood pressure lowering
• Improves overall cardiovascular health
• Simplifies medication regimen

Side Effects

• Dizziness
• Headache
• Fatigue
• Bradycardia (slow heart rate)
• Orthostatic hypotension
• Nausea
• Diarrhea
• Cough
• Muscle cramps
• Elevated potassium levels
• Swelling in ankles or feet
• Rash

Safety Measures

• Alcohol - Alcohol can potentiate the blood pressure-lowering effects of this medication, leading to increased dizziness or lightheadedness. Limit or avoid alcohol consumption.
• Pregnancy - Use during pregnancy is strongly contraindicated, especially in the second and third trimesters, due to severe risks to the fetus. Discontinue immediately if pregnancy is detected.
• Breastfeeding - Components of this medication may pass into breast milk. Use is generally not recommended; consult your doctor to discuss alternatives or risks.
• Liver - Use with caution in patients with liver impairment. Dose adjustment may be necessary, and liver function should be closely monitored due to potential for altered drug metabolism.
• Kidney - Use with extreme caution in patients with kidney impairment. Dose adjustment is often required, and renal function should be regularly monitored due to potential for worsening renal function.
• Lung - Caution is advised in patients with asthma, COPD, or other obstructive lung diseases, as the beta-blocker component can exacerbate bronchospasm.

Disclaimer

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