Novotaxel 120mg Injection

About

Novotaxel 120mg Injection is a potent antineoplastic agent belonging to the taxane class of chemotherapy drugs, widely used in the treatment of various solid tumors. Its mechanism of action involves interfering with the normal function of microtubules, which are critical components of the cell's cytoskeleton essential for cell division. By stabilizing microtubules and preventing their depolymerization, Novotaxel disrupts the dynamic equilibrium required for mitosis, leading to cell cycle arrest and ultimately inducing apoptosis (programmed cell death) in rapidly dividing cancer cells. This cytotoxic effect makes it highly effective against a broad spectrum of malignancies. It is administered intravenously under strict medical supervision, often as a key component of multi-drug chemotherapy regimens, requiring careful monitoring for efficacy and potential adverse reactions. Premedication is often necessary to mitigate hypersensitivity reactions.

Uses

• Treatment of breast cancer.
• Management of non-small cell lung cancer.
• Therapy for prostate cancer.
• Treatment of gastric adenocarcinoma.

Directions For Use

Administer intravenously by a qualified healthcare professional. Dosage and infusion schedule are determined by the oncologist based on patient factors.

Benefits

• Effective against various solid tumors.
• Induces cancer cell apoptosis.
• Can be used in combination therapies.
• May improve survival rates.
• Reduces tumor burden.
• Helps prevent disease progression.

Side Effects

• Myelosuppression (low blood counts).
• Peripheral neuropathy.
• Nausea and vomiting.
• Hair loss (alopecia).
• Fatigue.
• Fluid retention.
• Hypersensitivity reactions.
• Muscle and joint pain.
• Nail changes.
• Diarrhea.
• Oral mucositis.
• Liver enzyme elevation.

Safety Measures

• Alcohol - Avoid alcohol as it may exacerbate liver toxicity and gastrointestinal side effects associated with chemotherapy.
• Pregnancy - Contraindicated; can cause severe fetal harm. Use effective contraception during and after treatment.
• Breastfeeding - Not recommended; discontinue breastfeeding during treatment and for a period after the last dose.
• Liver - Use with extreme caution in patients with liver impairment; dosage adjustment is crucial due to increased toxicity risk.
• Kidney - Use with caution in patients with kidney impairment; monitor renal function closely and adjust dosage as needed.
• Lung - Monitor for interstitial pneumonitis or acute respiratory distress syndrome; report any new or worsening respiratory symptoms.

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