P4GEST GEL 10 S

About

Progesterone is a naturally occurring steroid hormone crucial for regulating the menstrual cycle, maintaining pregnancy, and supporting the development of female secondary sexual characteristics. P4GEST Gel is a specialized formulation designed for vaginal administration, allowing for direct and efficient delivery of progesterone to the uterine lining. This targeted approach is particularly beneficial for luteal phase support in assisted reproductive technologies (ART), where it helps prepare the endometrium for embryo implantation and fosters a conducive environment for early pregnancy. Furthermore, it is utilized in hormone replacement therapy and in certain cases for the prevention of preterm birth in high-risk women. By directly influencing the uterine tissue, the gel minimizes systemic absorption, thereby reducing the likelihood of widespread side effects often associated with oral progesterone, while ensuring optimal local therapeutic concentrations for reproductive health.

Uses

• Luteal phase support in ART.
• Hormone replacement therapy.
• Prevention of preterm birth in high-risk women.
• Management of secondary amenorrhea.

Directions For Use

Apply the prescribed amount of gel vaginally, usually once daily, as directed by your physician.

Benefits

• Supports uterine lining for implantation.
• Helps maintain early pregnancy.
• Reduces risk of preterm birth.
• Minimizes systemic side effects.
• Convenient vaginal administration.
• Effective in hormone replacement.

Side Effects

• Vaginal irritation or discharge.
• Headache.
• Nausea.
• Breast tenderness.
• Bloating.
• Mood changes.
• Fatigue.
• Dizziness.
• Abdominal pain.
• Hot flashes.
• Fluid retention.
• Allergic reactions (rare).

Safety Measures

• Alcohol - No known direct interaction; however, excessive alcohol may exacerbate some side effects like dizziness.
• Pregnancy - Essential for maintaining pregnancy; used under medical supervision, especially in early stages.
• Breastfeeding - Generally considered safe, but consult a doctor as small amounts may pass into breast milk.
• Liver - Use with caution in severe liver impairment; systemic absorption is minimal with vaginal gel.
• Kidney - Generally safe for use in kidney conditions; no dose adjustment typically required.
• Lung - No specific contraindications related to lung conditions.

Disclaimer

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