PACITANE TAB 30'S

About

PACITANE, containing Trihexyphenidyl, is an anticholinergic medication primarily used to treat symptoms of Parkinson's disease and drug-induced extrapyramidal symptoms. It works by blocking the action of acetylcholine in the brain, thereby helping to restore the balance between acetylcholine and dopamine, which is often disrupted in these conditions. This action leads to a reduction in muscle stiffness, tremors, and other involuntary movements. Trihexyphenidyl can alleviate symptoms such as rigidity, bradykinesia (slowness of movement), and dystonia (sustained muscle contractions). It is particularly useful for managing the motor fluctuations and dyskinesias that can arise from long-term levodopa therapy or as side effects of antipsychotic medications. Its central anticholinergic effects contribute to improved motor control and overall quality of life for affected individuals.

Uses

• Treatment of Parkinson's disease.
• Management of drug-induced extrapyramidal symptoms.
• Relief from dystonia and akathisia.
• Reduction of tremors and rigidity.

Directions For Use

Take orally, usually 3-4 times daily, with or after meals to minimize gastrointestinal upset, or as prescribed by your physician.

Benefits

• Reduces the severity of tremors.
• Alleviates muscle rigidity and stiffness.
• Helps control involuntary movements.
• Improves gait and motor function.
• Decreases excessive drooling.
• Enhances overall physical mobility.

Side Effects

• Dry mouth and blurred vision.
• Constipation and urinary retention.
• Dizziness and drowsiness.
• Nausea and vomiting.
• Nervousness or agitation.
• Confusion and memory impairment.
• Tachycardia (rapid heart rate).
• Dilated pupils (mydriasis).
• Headache.
• Difficulty swallowing.
• Skin rash.
• Weakness.

Safety Measures

• Alcohol - Avoid alcohol consumption as it can increase CNS depression and drowsiness, exacerbating side effects.
• Pregnancy - Use only if clearly needed and potential benefits outweigh risks; potential fetal harm is not fully established. Consult a doctor.
• Breastfeeding - Not recommended as it may reduce milk production and potentially cause adverse effects in the infant.
• Liver - Use with caution in patients with liver impairment; dose adjustment may be needed in severe cases.
• Kidney - Use with caution in patients with kidney impairment; dose adjustment may be needed in severe cases.
• Lung - Use with caution in patients with chronic lung disease due to potential for respiratory depression or exacerbation of symptoms.

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