About
POMEROZ CAP, which is Omeprazole, is a highly effective proton pump inhibitor (PPI) specifically designed to profoundly reduce the production of gastric acid in the stomach. Its mechanism of action involves an irreversible binding to and inhibition of the H+/K+-ATPase enzyme system, commonly known as the proton pump, located within the secretory canaliculi of the gastric parietal cells. By blocking this final common pathway of acid secretion, Omeprazole achieves a significant and sustained reduction in gastric acid output. This potent acid-suppressing effect makes it exceptionally valuable in the treatment of conditions exacerbated by excessive stomach acid, such as gastroesophageal reflux disease (GERD), peptic ulcers (both gastric and duodenal), and Zollinger-Ellison syndrome. It effectively promotes the healing of erosions and provides substantial relief from associated symptoms like heartburn. While generally well-tolerated for short-term use, prolonged therapy warrants careful consideration of potential long-term side effects.
Uses
- Treatment of gastroesophageal reflux disease (GERD).
- Healing of gastric and duodenal ulcers.
- Eradication of Helicobacter pylori (in combination therapy).
- Management of Zollinger-Ellison syndrome.
Directions For Use
Take one capsule daily, preferably in the morning before a meal, or as directed by your doctor. Swallow whole.
Benefits
- Highly effective in reducing stomach acid.
- Provides significant relief from heartburn and acid reflux.
- Promotes healing of esophageal and gastric erosions.
- Helps prevent recurrence of ulcers.
- Convenient once-daily dosing.
- Well-established safety profile for short-term use.
Side Effects
- Headache
- Nausea
- Diarrhea
- Abdominal pain
- Constipation
- Flatulence
- Vomiting
- Dizziness
- Rash
- Dry mouth
- Fatigue
- Increased risk of C. difficile infection (long-term)
Safety Measures
- Alcohol - Generally safe to consume alcohol in moderation, but excessive alcohol can irritate the stomach and worsen acid reflux symptoms.
- Pregnancy - Generally considered safe for use during pregnancy, but always consult a doctor to weigh benefits against potential risks.
- Breastfeeding - Passes into breast milk in small amounts; generally considered compatible with breastfeeding, but consult a physician.
- Liver - Use with caution in patients with severe liver impairment; dose adjustment may be necessary due to altered metabolism.
- Kidney - Generally safe for use in patients with kidney conditions; no dose adjustment typically required for mild to moderate impairment.
- Lung - No specific contraindications related to lung conditions. May help reduce aspiration risk in severe reflux.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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