PROXIDOM 500 MG TAB 10

About

PROXIDOM 500 MG TAB is a combination medication often prescribed for conditions requiring both pain relief and anti-nausea effects, such as migraine headaches. It typically contains Naproxen, a non-steroidal anti-inflammatory drug (NSAID), and Domperidone, a dopamine antagonist with antiemetic and prokinetic properties. Naproxen provides potent analgesic and anti-inflammatory effects by inhibiting prostaglandin synthesis, effectively reducing pain and inflammation. Domperidone works by blocking dopamine receptors in the chemoreceptor trigger zone, thereby alleviating nausea and vomiting, and also enhances gastrointestinal motility, which can be beneficial in conditions like migraine where gastric stasis is common. This synergistic combination offers comprehensive relief for symptoms that often co-occur, improving patient comfort and recovery.

Uses

• Migraine headaches with nausea
• Tension headaches with gastric discomfort
• Musculoskeletal pain with associated nausea
• Dysmenorrhea with nausea and vomiting

Directions For Use

Take one tablet orally, once or twice daily, preferably before meals, or as directed by your physician.

Benefits

• Effective pain relief
• Reduces inflammation
• Alleviates nausea and vomiting
• Improves gastric motility
• Long-lasting action
• Comprehensive relief for migraine symptoms

Side Effects

• Nausea
• Abdominal pain
• Dyspepsia
• Heartburn
• Headache
• Dizziness
• Drowsiness
• Dry mouth
• Rash
• Constipation
• Diarrhea
• Fluid retention

Safety Measures

• Alcohol - Avoid or limit alcohol intake due to increased risk of stomach irritation and potential liver damage.
• Pregnancy - Avoid, especially in the third trimester; consult your doctor. Domperidone use should be cautious.
• Breastfeeding - Not recommended during breastfeeding as both components can pass into breast milk and affect the infant.
• Liver - Use with caution in patients with liver conditions; avoid in severe liver disease.
• Kidney - Use with caution; NSAIDs can impair renal function, and Domperidone requires dose adjustment in renal impairment.
• Lung - Use with caution in asthma patients due to the potential for NSAID-induced bronchospasm.

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