REKOOL 40 15S

About

REKOOL 40 typically refers to a proton pump inhibitor (PPI) medication, such as Rabeprazole, Pantoprazole, or Omeprazole, at a strength of 40mg. PPIs work by irreversibly binding to and inhibiting the H+/K+-ATPase enzyme system, commonly known as the proton pump, located in the secretory canaliculi of the gastric parietal cells. This inhibition effectively blocks the final step in gastric acid production, leading to a significant and prolonged reduction in stomach acid secretion. This mechanism makes PPIs highly effective in treating a range of acid-related gastrointestinal disorders.

The 40mg strength is often prescribed for more severe or refractory conditions where a higher degree of acid suppression is required. It is used to treat conditions such as severe gastroesophageal reflux disease (GERD), erosive esophagitis, peptic ulcers (gastric and duodenal), and Zollinger-Ellison syndrome. By reducing acid levels, it helps alleviate symptoms like heartburn, acid regurgitation, and epigastric pain, while also promoting the healing of damaged esophageal and gastric mucosa. Long-term use may require monitoring for potential side effects.

Uses

• Treatment of severe gastroesophageal reflux disease (GERD).
• Healing of erosive esophagitis.
• Management of peptic ulcers (gastric and duodenal).
• Treatment of Zollinger-Ellison syndrome.

Directions For Use

Take one capsule/tablet once daily, preferably before breakfast, or as directed by your physician.

Benefits

• Potently reduces stomach acid production.
• Provides effective relief from severe heartburn.
• Promotes rapid healing of esophageal erosions.
• Helps prevent recurrence of peptic ulcers.
• Alleviates symptoms of acid regurgitation.
• Offers sustained acid suppression for severe conditions.

Side Effects

• Headache
• Nausea
• Diarrhea
• Abdominal pain
• Flatulence
• Constipation
• Dizziness
• Dry mouth
• Skin rash
• Fatigue
• Insomnia
• Bone fractures (with long-term high dose use)

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can irritate the stomach lining and worsen acid reflux symptoms.
• Pregnancy - Consult your doctor before use; generally considered safe but use only if clearly needed.
• Breastfeeding - Consult your doctor; generally considered safe but use with caution.
• Liver - Use with caution in patients with severe liver impairment; dose adjustment may be necessary.
• Kidney - Generally safe for use in patients with kidney conditions; no specific dose adjustment usually required.
• Lung - Long-term PPI use may be associated with an increased risk of community-acquired pneumonia.

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