RABIPLUS D CAP 10S

About

RABIPLUS D CAP is a combination medication containing Rabeprazole, a proton pump inhibitor (PPI), and Domperidone, a prokinetic and antiemetic agent. Rabeprazole effectively reduces the production of stomach acid by inhibiting the H+/K+-ATPase enzyme system in the gastric parietal cells. This mechanism is crucial for treating conditions like GERD and peptic ulcers. Domperidone works by blocking dopamine receptors in the chemoreceptor trigger zone and in the gastrointestinal tract, which helps to increase gastric motility, accelerate gastric emptying, and alleviate nausea and vomiting. This synergistic action provides comprehensive relief for conditions involving both excessive acid secretion and impaired gastrointestinal motility, offering a robust solution for various upper digestive complaints.

Uses

• Treatment of gastroesophageal reflux disease (GERD).
• Management of dyspepsia (indigestion).
• Relief from nausea and vomiting.
• Healing of peptic ulcers.

Directions For Use

Take orally once daily, typically before a meal, usually in the morning, as directed by your healthcare provider.

Benefits

• Effectively reduces stomach acid production.
• Alleviates heartburn and acid reflux symptoms.
• Improves gastric emptying and motility.
• Controls nausea and vomiting.
• Provides sustained relief from digestive discomfort.
• Aids in the healing of esophageal erosions and ulcers.

Side Effects

• Headache
• Diarrhea
• Nausea
• Abdominal pain
• Flatulence
• Dry mouth
• Dizziness
• Constipation
• Skin rash
• Gynecomastia (Domperidone)
• QT prolongation (Domperidone, rare)
• Vitamin B12 deficiency (long-term PPI use)
• Insomnia

Safety Measures

• Alcohol - Alcohol may irritate the stomach lining and potentially worsen symptoms, counteracting the medication's effects. Moderate intake is advised.
• Pregnancy - Use with caution during pregnancy. Consult your doctor to weigh the potential benefits against any risks to the fetus.
• Breastfeeding - Domperidone passes into breast milk. Use with caution, and consult your doctor before breastfeeding while on this medication.
• Liver - Use with caution in patients with liver impairment. Dosage adjustments may be necessary, especially for Domperidone, due to altered metabolism.
• Kidney - Use with caution in patients with severe renal impairment. Dosage adjustments may be required, particularly for Domperidone.
• Lung - No direct specific interaction. However, effective management of GERD can reduce the risk of aspiration-related lung complications.

Disclaimer

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