REKOOL D 40 10'S

About

REKOOL D 40 is a combination medication containing a proton pump inhibitor (PPI), typically Rabeprazole or Pantoprazole 40mg, and the prokinetic agent Domperidone. The PPI component works by potently inhibiting the H+/K+-ATPase enzyme system, also known as the proton pump, in the gastric parietal cells. This action leads to a significant and sustained reduction in gastric acid secretion, making it highly effective in treating conditions like severe gastroesophageal reflux disease (GERD), erosive esophagitis, and peptic ulcers. Domperidone, a peripheral dopamine D2 receptor antagonist, enhances gastrointestinal motility by increasing the tone of the lower esophageal sphincter and accelerating gastric emptying without affecting gastric acid secretion.

The combined action of these two agents provides comprehensive management for complex upper gastrointestinal disorders. The PPI effectively controls acid-related symptoms such as severe heartburn, acid regurgitation, and epigastric pain, while Domperidone addresses symptoms related to impaired gastric motility, including nausea, vomiting, bloating, and a feeling of fullness. This formulation is particularly beneficial for patients who experience both excessive acid production and delayed gastric emptying, offering superior symptom relief and promoting healing of the esophageal and gastric mucosa.

Uses

• Severe gastroesophageal reflux disease (GERD).
• Management of erosive esophagitis.
• Treatment of peptic ulcers with associated motility issues.
• Relief from severe dyspepsia, nausea, and vomiting.

Directions For Use

Take one capsule once daily, preferably before breakfast, or as advised by your doctor.

Benefits

• Potently reduces stomach acid production.
• Provides rapid and sustained relief from heartburn.
• Accelerates gastric emptying and improves motility.
• Effectively reduces nausea and vomiting.
• Promotes healing of esophageal and gastric lesions.
• Offers comprehensive relief for complex GI symptoms.

Side Effects

• Headache
• Nausea
• Diarrhea
• Abdominal pain
• Dry mouth
• Flatulence
• Dizziness
• Constipation
• Skin rash
• Insomnia
• Breast tenderness (due to Domperidone)
• QT prolongation (rare, due to Domperidone)

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can irritate the stomach lining and worsen acid reflux symptoms.
• Pregnancy - Consult your doctor before use; generally not recommended unless clearly necessary.
• Breastfeeding - Not recommended during breastfeeding as Domperidone can pass into breast milk.
• Liver - Use with caution in patients with severe liver impairment; dose adjustment may be necessary.
• Kidney - Use with caution in patients with severe kidney impairment; dose adjustment may be necessary.
• Lung - No specific contraindications, but long-term PPI use may be associated with increased risk of pneumonia.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.