ROXID 300 10'S

About

Roxithromycin 300 mg is a macrolide antibiotic, belonging to a class of drugs that inhibit bacterial protein synthesis. It achieves its antibacterial effect by binding to the 50S ribosomal subunit of susceptible bacteria, thereby preventing the translation of messenger RNA and the subsequent formation of proteins essential for bacterial growth and replication. This bacteriostatic action makes it effective against a wide range of Gram-positive and some Gram-negative bacteria, as well as atypical pathogens like Mycoplasma and Chlamydia. Roxithromycin is often chosen as an alternative for patients who are allergic to penicillin or for infections where penicillin is not the most appropriate choice, offering a valuable therapeutic option with good tissue penetration.

Uses

• Respiratory tract infections
• Skin and soft tissue infections
• Genitourinary infections
• Ear, nose, and throat infections

Directions For Use

Take one tablet daily, preferably before a meal, or as directed by your doctor. Do not exceed the prescribed dosage.

Benefits

• Effective against atypical pathogens
• Good tissue penetration
• Suitable for penicillin-allergic patients
• Generally well-tolerated
• Convenient once-daily dosing
• Broad spectrum of activity

Side Effects

• Nausea
• Vomiting
• Abdominal pain
• Diarrhea
• Headache
• Dizziness
• Rash
• Elevated liver enzymes
• Candidiasis
• Taste disturbance
• Prolonged QT interval
• Allergic reactions

Safety Measures

• Alcohol - Avoid excessive alcohol consumption as it may increase the risk of gastrointestinal side effects or liver strain.
• Pregnancy - Use with caution during pregnancy; consult a doctor to assess the risk-benefit ratio before use.
• Breastfeeding - Roxithromycin is excreted in breast milk; monitor the infant for gastrointestinal disturbances. Use only if clearly necessary.
• Liver - Use with caution in patients with severe hepatic impairment; dose adjustment may be required, and liver function should be monitored.
• Kidney - No dose adjustment is typically required for mild to moderate renal impairment, but caution is advised in severe cases.
• Lung - Generally safe for use in patients with lung conditions, but caution is advised in those with pre-existing cardiac arrhythmias.

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