About

S-ZETALO PLUS is a combination medication comprising escitalopram, a selective serotonin reuptake inhibitor (SSRI), and clonazepam, a benzodiazepine. Escitalopram functions by increasing the availability of serotonin in the brain, which is crucial for mood regulation and anxiety reduction. Clonazepam acts on gamma-aminobutyric acid (GABA) receptors, enhancing its inhibitory effects, leading to a calming, anxiolytic, and muscle-relaxant action. This synergistic approach allows for comprehensive management of conditions where both mood and anxiety symptoms are prominent.

This formulation is commonly prescribed for the treatment of anxiety disorders, panic attacks, and depressive episodes accompanied by significant anxiety or agitation. The clonazepam component provides rapid symptomatic relief from acute anxiety and panic, while escitalopram addresses the underlying neurochemical imbalances over the longer term, offering a dual approach to treatment. Due to the potential for dependence associated with benzodiazepines, the clonazepam component is typically used for short durations or as an initial bridging therapy, with careful monitoring and gradual tapering.

Uses

Treatment of generalized anxiety disorder.
Management of panic disorder.
Treatment of major depressive disorder with anxiety.
Short-term relief of severe anxiety symptoms.

Directions For Use

Take this medication orally, usually once daily, with or without food, as directed by your healthcare provider. Do not discontinue abruptly.

Benefits

Rapidly alleviates acute anxiety and panic symptoms.
Provides long-term management for depression and anxiety.
Effectively targets both emotional and physical anxiety manifestations.
Helps stabilize mood and reduce the frequency of panic attacks.
Improves overall mental well-being and daily functioning.
Offers a comprehensive approach to anxiety-related conditions.

Side Effects

Drowsiness, sedation
Dizziness, lightheadedness
Nausea, dry mouth
Fatigue, weakness
Blurred vision
Constipation or diarrhea
Sexual dysfunction (escitalopram)
Weight changes
Insomnia or vivid dreams
Tremor
Memory impairment
Withdrawal symptoms upon abrupt discontinuation

Safety Measures

Alcohol - Avoid alcohol consumption entirely as it significantly potentiates the sedative effects of clonazepam, increasing risks of severe drowsiness and respiratory depression.
Pregnancy - Both escitalopram and clonazepam carry risks during pregnancy, including congenital malformations (clonazepam) and neonatal adaptation syndrome (escitalopram). Use only if benefits clearly outweigh risks.
Breastfeeding - Both components are excreted into breast milk. Potential for sedation or feeding difficulties in the infant. Consult a doctor; generally not recommended.
Liver - Use with caution in patients with hepatic impairment, as metabolism of both drugs can be affected, potentially leading to increased drug levels and adverse effects. Dose adjustment may be necessary.
Kidney - Use with caution in patients with renal impairment. Dose adjustment may be required, especially for clonazepam, to prevent accumulation.
Lung - Use with extreme caution in patients with severe respiratory conditions (e.g., COPD, sleep apnea) due to the risk of respiratory depression from clonazepam.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.

Shipping & Location