SIBELIUM 5MG TAB

About

Sibelium 5mg, containing Flunarizine, is a selective calcium entry blocker with calmodulin binding properties, primarily used for the prophylactic treatment of migraine and the symptomatic treatment of vertigo. It works by stabilizing vascular tone and preventing excessive vasoconstriction, which is believed to be a key mechanism in migraine pathogenesis. Flunarizine also exhibits vestibular suppressant properties, making it effective in managing various forms of vertigo, including Meniere's disease and vestibular migraine.

Its action is primarily preventive, aiming to reduce the frequency and severity of attacks rather than providing acute relief. The medication helps to improve cerebral blood flow and protect brain cells from damage during ischemic events. Due to its long half-life, it is typically administered once daily, often at bedtime, to minimize potential sedative effects. Clinical efficacy is usually observed after several weeks of consistent use.

Uses

• Prophylaxis of migraine headaches
• Symptomatic treatment of vertigo
• Management of Meniere's disease
• Adjunctive therapy in cerebrovascular disorders

Directions For Use

Take one tablet orally, usually once daily at bedtime, as prescribed by your doctor.

Benefits

• Reduces the frequency of migraine attacks
• Decreases the severity of migraine headaches
• Alleviates symptoms of vertigo and dizziness
• Improves overall quality of life for migraineurs
• Non-addictive and generally well-tolerated
• Provides sustained prophylactic action

Side Effects

• Drowsiness or sedation
• Weight gain
• Depression
• Fatigue
• Nausea
• Stomach upset
• Insomnia
• Anxiety
• Muscle aches
• Extrapyramidal symptoms (rare)
• Dry mouth
• Skin rash

Safety Measures

• Alcohol - Avoid or limit alcohol consumption due to increased risk of drowsiness and central nervous system depression.
• Pregnancy - Not recommended during pregnancy unless clearly necessary and benefits outweigh risks; consult your doctor.
• Breastfeeding - Not recommended during breastfeeding as Flunarizine may pass into breast milk; consult your doctor.
• Liver - Use with caution in patients with liver impairment; dose adjustment may be necessary.
• Kidney - Generally safe in kidney conditions, but caution is advised in severe impairment; consult your doctor.
• Lung - No specific contraindications or precautions related to lung conditions are generally associated with Flunarizine.

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