Soralieva 200mg Tablet

About

Sorafenib 200mg Tablet is an advanced oral multi-kinase inhibitor specifically designed for the targeted treatment of certain aggressive cancers. It functions by simultaneously inhibiting multiple intracellular and cell surface kinases, which are crucial for both tumor cell proliferation and the process of angiogenesis, the formation of new blood vessels that feed tumors. This dual mechanism of action effectively disrupts cancer growth pathways and starves tumors of their blood supply, leading to a significant slowdown in disease progression and, in some cases, tumor regression in specific malignancies like hepatocellular carcinoma, renal cell carcinoma, and differentiated thyroid carcinoma.

Administered under the strict guidance of an oncologist, this medication necessitates meticulous patient monitoring due to its potent pharmacological profile and the potential for a range of significant adverse effects. Adherence to the prescribed dosage and treatment schedule is paramount for optimizing therapeutic outcomes and effectively managing any emerging side reactions. Patients undergoing treatment with Sorafenib must commit to regular clinical assessments, including laboratory tests and imaging studies, to ensure safety and efficacy throughout the course of therapy.

Uses

• Treatment of unresectable hepatocellular carcinoma (HCC).
• Treatment of advanced renal cell carcinoma (RCC).
• Treatment of differentiated thyroid carcinoma (DTC) refractory to radioactive iodine.
• Used when other treatments have failed or are not suitable.

Directions For Use

Take orally, usually twice daily, on an empty stomach or with a low-fat meal. Swallow the tablet whole with water.

Benefits

• Slows the progression of certain advanced cancers.
• Extends overall survival in specific patient populations.
• Targets multiple pathways involved in cancer growth.
• Available as an oral tablet for convenient administration.
• Offers a treatment option for difficult-to-treat cancers.
• Can improve quality of life by managing disease symptoms.

Side Effects

• Diarrhea
• Hand-foot skin reaction (palmar-plantar erythrodysesthesia)
• Fatigue
• Rash
• Hypertension (high blood pressure)
• Nausea
• Vomiting
• Anorexia (loss of appetite)
• Weight loss
• Hair loss (alopecia)
• Bleeding events
• Hypophosphatemia

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it may exacerbate liver toxicity or other side effects. Consult your doctor.
• Pregnancy - Sorafenib is contraindicated in pregnancy due to potential fetal harm. Effective contraception is required during treatment and for a period after.
• Breastfeeding - Breastfeeding is not recommended during treatment with Sorafenib and for a period after the last dose due to potential harm to the infant.
• Liver - Use with caution in patients with liver impairment; dose adjustments may be necessary. Close monitoring of liver function is essential.
• Kidney - Use with caution in patients with severe kidney impairment. No specific dose adjustment is typically required for mild to moderate impairment.
• Lung - Rare but serious lung toxicities, including interstitial lung disease, have been reported. Monitor for new or worsening respiratory symptoms.

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