SUMO TAB 15 S

About

SUMO TAB, containing Nimesulide, is a non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. It primarily acts as a selective inhibitor of cyclooxygenase-2 (COX-2), an enzyme responsible for the synthesis of prostaglandins involved in pain, inflammation, and fever. By selectively targeting COX-2, Nimesulide aims to reduce inflammatory responses with a potentially lower risk of gastrointestinal side effects compared to non-selective NSAIDs, although this benefit is debated. It is widely used for the symptomatic treatment of acute pain, osteoarthritis, and primary dysmenorrhea. Its rapid onset of action and effective pain relief make it a popular choice for various inflammatory and painful conditions. However, its use is restricted in some countries due to concerns regarding liver toxicity.

Uses

• Relief from acute pain.
• Symptomatic treatment of osteoarthritis.
• Management of primary dysmenorrhea.
• Reduction of fever (in some regions).

Directions For Use

Take orally after meals, as directed by your physician, to minimize gastrointestinal irritation.

Benefits

• Provides effective pain relief.
• Reduces inflammation.
• Lowers fever.
• Rapid onset of action.
• Generally well-tolerated for short-term use.
• Convenient dosing regimen.

Side Effects

• Nausea and vomiting.
• Stomach pain or discomfort.
• Diarrhea.
• Heartburn or indigestion.
• Dizziness or headache.
• Skin rash or itching.
• Allergic reactions.
• Elevated liver enzymes.
• Gastrointestinal bleeding (rare).
• Fluid retention and edema.
• Ulcers.
• Jaundice (rare).

Safety Measures

• Alcohol - Avoid or limit alcohol consumption due to increased risk of stomach irritation and potential for liver damage.
• Pregnancy - Not recommended, especially in the third trimester, due to potential fetal harm and complications during delivery. Consult a doctor.
• Breastfeeding - Not recommended; Nimesulide may pass into breast milk and cause adverse effects in the infant.
• Liver - Contraindicated in severe liver impairment; use with extreme caution and monitor liver function closely in all patients.
• Kidney - Use with caution; dose adjustment may be needed in patients with impaired kidney function due to risk of renal toxicity.
• Lung - Caution in patients with asthma, especially aspirin-sensitive asthma, due to the risk of inducing bronchospasm.

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