TELMA AZ 40 10

About

TELMA AZ 40 is a fixed-dose combination medication designed for the effective management of essential hypertension. It typically combines an angiotensin II receptor blocker (ARB) such as Telmisartan 40mg with a dihydropyridine calcium channel blocker (CCB) like Azelnidipine. Telmisartan works by blocking the effects of angiotensin II, leading to vasodilation and a reduction in blood pressure. Azelnidipine complements this action by blocking calcium channels in vascular smooth muscle, further promoting vasodilation and lowering peripheral resistance.

This synergistic combination provides robust blood pressure control, particularly beneficial for patients who require more than one agent to achieve their target blood pressure. The dual mechanism helps to reduce the overall cardiovascular risk associated with hypertension. It also offers the advantage of potentially reducing the incidence of dose-dependent side effects that might occur with higher doses of individual components. Adherence to the prescribed regimen and regular medical follow-ups are crucial for optimal therapeutic outcomes.

Uses

• Treatment of essential hypertension.
• Management of uncontrolled hypertension.
• Reduction of cardiovascular risk.
• Adjunctive therapy for patients with multiple risk factors.

Directions For Use

Take one tablet orally once daily, at the same time each day, with or without food, as prescribed by your doctor. Swallow the tablet whole with water.

Benefits

• Effective and sustained blood pressure control.
• Dual mechanism for comprehensive action.
• Reduces the risk of cardiovascular events.
• May minimize CCB-related peripheral edema.
• Convenient once-daily dosing.
• Improved patient adherence.

Side Effects

• Dizziness.
• Headache.
• Peripheral edema.
• Fatigue.
• Hypotension.
• Nausea.
• Diarrhea.
• Hyperkalemia.
• Palpitations.
• Flushing.
• Back pain.
• Upper respiratory tract infection.

Safety Measures

• Alcohol - Alcohol can increase the hypotensive effect and risk of dizziness; use with caution and limit intake.
• Pregnancy - Contraindicated during the second and third trimesters due to the risk of fetal injury and death from the ARB.
• Breastfeeding - Not recommended; consider alternative treatments or discontinue breastfeeding due to potential infant exposure.
• Liver - Use with caution in patients with hepatic impairment; dose adjustment may be necessary.
• Kidney - Monitor renal function closely, especially in patients with pre-existing renal impairment or renal artery stenosis.
• Lung - Generally safe for patients with lung conditions as it does not directly affect respiratory function.

Disclaimer

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