TENVIR TAB 30

About

Tenofovir disoproxil fumarate (TDF) is a nucleotide reverse transcriptase inhibitor (NtRTI) used in the treatment of human immunodeficiency virus (HIV) infection and chronic hepatitis B virus (HBV) infection. It works by interfering with the reverse transcriptase enzyme, which is crucial for the replication of both HIV and HBV. By inhibiting this enzyme, TDF prevents the viruses from multiplying and spreading in the body, thereby reducing viral load and improving immune function in HIV patients, and suppressing viral replication in HBV patients.

TDF is often part of a combination therapy for HIV, contributing to highly active antiretroviral therapy (HAART) regimens. For chronic HBV, it is a potent antiviral agent that can lead to sustained viral suppression and improve liver histology. Regular monitoring of kidney function and bone mineral density is important during treatment due to potential side effects. Its efficacy and relatively good tolerability have made it a cornerstone in the management of these chronic viral infections.

Uses

• Treatment of HIV-1 infection in adults and pediatric patients.
• Treatment of chronic hepatitis B virus (HBV) infection.
• Pre-exposure prophylaxis (PrEP) for HIV prevention.
• Post-exposure prophylaxis (PEP) for HIV prevention.

Directions For Use

Take one tablet once daily with food, or as directed by your healthcare provider.

Benefits

• Potent antiviral activity against HIV and HBV.
• Reduces viral load in HIV-infected individuals.
• Suppresses HBV replication and improves liver health.
• Used in combination therapies for HIV.
• Effective for HIV pre-exposure prophylaxis (PrEP).
• Generally well-tolerated with daily dosing.

Side Effects

• Nausea
• Diarrhea
• Vomiting
• Abdominal pain
• Headache
• Dizziness
• Fatigue
• Rash
• Kidney impairment (nephrotoxicity)
• Decreased bone mineral density
• Lactic acidosis (rare but serious)
• Pancreatitis (rare)

Safety Measures

• Alcohol - Alcohol consumption should be avoided or minimized, especially in patients with HIV or HBV, as it can worsen liver disease and overall health.
• Pregnancy - Generally considered safe for use during pregnancy for HIV treatment, but always consult a doctor to weigh benefits against risks.
• Breastfeeding - Not recommended for breastfeeding mothers with HIV due to the risk of HIV transmission to the infant and potential drug exposure.
• Liver - Used for HBV, but caution is advised in patients with pre-existing liver disease; monitor liver function regularly.
• Kidney - Requires careful monitoring of kidney function before and during treatment; dose adjustment may be necessary in renal impairment.
• Lung - No specific safety concerns or contraindications related to lung conditions are generally associated with tenofovir.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.