About
Tepastim 15mg Injection is an antineoplastic medication containing the active ingredient Thiotepa. It is prescribed alongside other anticancer drugs before stem cell transplantation in adult patients with cancer affecting the lymph nodes of the central nervous system. This injection is also used as a preparatory treatment to reduce the risk of graft rejection during stem cell transplants. Additionally, it helps manage fluid buildup caused by cancer in the serous membranes and is indicated for treating breast, ovarian, and bladder cancers. Common side effects may include diarrhea, rashes, bleeding, blood in the urine, and cytomegalovirus infection. If you experience any of these symptoms persistently or severely, inform your doctor promptly.
Make sure to notify your healthcare provider if you are allergic to Thiotepa or any ingredients in the injection. Tepastim is contraindicated for patients receiving live virus or bacterial vaccines, including the yellow fever vaccine. If you have a history of heart, liver, kidney, or lung diseases, or if you suffer from severe myelosuppression (such as anemia, neutropenia, or thrombocytopenia), inform your doctor. Regular monitoring of liver and heart function is necessary, and caution should be exercised in patients with cardiac or liver conditions. This medication is not recommended for use during pregnancy or breastfeeding.
Uses
- Preparation for allogeneic hematopoietic stem cell transplantation in pediatric patients with class 3 beta-thalassemia
- Treatment of adenocarcinoma of breast and ovary.
- Treatment of superficial papillary cancer of the urinary bladder.
Directions for use
This medicine will be administered by your doctor or nurse. Please do not attempt to self-administer it.
Side effects
- Severe drop in blood cell count
- Heart problem
- Kidney damage
- Nerve damage
- Lung toxicity
- Liver toxicity
- Cytomegalovirus infection
- Hemorrhage
- Diarrhea
- Blood in urine
- Rashes
Safety Measures
Alcohol - It is not known whether consuming alcohol is safe while taking Tepastim 15mg Injection. Speak with your doctor for guidance.
Pregnancy - Tepastim 15mg Injection is not safe to use during pregnancy as it may harm the fetus. Consult your doctor before using this medication if you are pregnant or planning to become pregnant.
Breastfeeding - Breastfeeding is not recommended during treatment with Tepastim 15mg Injection. Please consult your doctor before breastfeeding.
Liver - Inform your doctor if you have any liver issues before starting Tepastim 15mg Injection. Regular monitoring of liver function is essential during treatment.
Kidney - Use Tepastim 15mg Injection with caution if you have kidney problems, and inform your healthcare provider so they can monitor your kidney function during treatment.
Disclaimer
Med E Hub is committed to delivering reliable, expert-reviewed information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment.
Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
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