About
Ursodeoxycholic acid (UDCA) is a naturally occurring bile acid that is used to treat various liver and gallbladder conditions. It works by reducing the cholesterol content of bile, thereby facilitating the dissolution of cholesterol gallstones. UDCA also has cytoprotective, anti-inflammatory, and immunomodulatory properties, which are beneficial in managing cholestatic liver diseases. It helps to improve bile flow and protect liver cells from damage caused by toxic bile acids.
In conditions like primary biliary cholangitis (PBC), UDCA can slow disease progression and improve liver function tests. Its mechanism involves altering the composition of bile, making it less lithogenic, and promoting the excretion of toxic bile acids. This therapeutic action helps to alleviate symptoms and prevent further liver damage, making it a cornerstone in the management of specific hepatobiliary disorders.
Uses
- Dissolution of cholesterol gallstones.
- Treatment of primary biliary cholangitis (PBC).
- Management of cholestatic liver diseases.
- Prevention of gallstone formation in rapid weight loss.
Directions For Use
Take as directed by your physician, usually with food. Do not crush or chew the tablets.
Benefits
- Dissolves cholesterol gallstones effectively.
- Improves liver function in cholestatic conditions.
- Reduces inflammation and protects liver cells.
- Slows progression of primary biliary cholangitis.
- Enhances bile flow and reduces bile acid toxicity.
- May prevent gallstone recurrence after surgery.
Side Effects
- Diarrhea
- Nausea
- Abdominal pain
- Constipation
- Indigestion
- Headache
- Dizziness
- Skin rash
- Hair thinning
- Vomiting
- Fatigue
- Back pain
Safety Measures
- Alcohol - Alcohol consumption should be avoided or minimized as it can exacerbate liver conditions and potentially reduce the efficacy of the medication.
- Pregnancy - Use during pregnancy only if clearly needed and the potential benefits outweigh the risks, as limited data are available. Consult a doctor.
- Breastfeeding - Small amounts may pass into breast milk; use with caution and under medical supervision.
- Liver - Generally used to treat liver conditions, but severe liver impairment may require dose adjustment or careful monitoring.
- Kidney - No specific dose adjustment is typically required for kidney impairment, but caution is advised in severe cases.
- Lung - No direct contraindications or specific safety notes related to lung conditions are generally associated with this medication.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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