VALENCE OD 750 TAB 10 S

About

Valence OD 750 Tablet contains Valproic acid, an antiepileptic drug (AED) also known as a mood stabilizer. Its precise mechanism of action is not fully understood but is thought to involve increasing the levels of gamma-aminobutyric acid (GABA) in the brain, an inhibitory neurotransmitter, thereby reducing neuronal excitability. It may also modulate voltage-gated sodium channels and T-type calcium channels. This medication is widely used in the treatment of various seizure disorders, including generalized tonic-clonic, absence, and complex partial seizures. Furthermore, its mood-stabilizing properties make it effective in managing manic episodes associated with bipolar disorder and for the prophylaxis of migraine headaches. The "OD" (Once Daily) formulation provides sustained release, helping to maintain stable drug levels and improve patient adherence.

Uses

• Treatment of various types of epilepsy and seizures.
• Management of manic episodes in bipolar disorder.
• Prophylaxis of migraine headaches.
• Adjunctive therapy for certain psychiatric conditions.

Directions For Use

Take one tablet orally once daily, with or without food, as prescribed by your doctor. Swallow whole, do not crush or chew.

Benefits

• Effectively controls various seizure types.
• Stabilizes mood in bipolar disorder.
• Reduces frequency and severity of migraine attacks.
• Once-daily dosing for convenience.
• Helps prevent mood swings.
• Provides broad-spectrum antiepileptic activity.

Side Effects

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Drowsiness
• Tremor
• Hair loss
• Weight gain
• Thrombocytopenia
• Liver dysfunction (rare but serious)
• Pancreatitis (rare but serious)
• Neural tube defects in pregnancy (serious)

Safety Measures

• Alcohol - Avoid alcohol as it can increase central nervous system depression and exacerbate side effects like drowsiness and dizziness.
• Pregnancy - Contraindicated in pregnancy for migraine prophylaxis and for bipolar disorder unless no other effective treatment exists due to high risk of neural tube defects and other developmental abnormalities.
• Breastfeeding - Excreted into breast milk; use with caution and under medical supervision, monitoring the infant for sedation.
• Liver - Contraindicated in patients with significant hepatic dysfunction or disease; monitor liver function closely.
• Kidney - Use with caution in patients with kidney impairment; dosage adjustments may be necessary.
• Lung - No specific contraindications, but monitor for respiratory depression if combined with other CNS depressants.

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