About

Betahistine is a histamine analog primarily used to treat symptoms associated with Meniere's disease, including vertigo, tinnitus, and progressive hearing loss. Its therapeutic action is believed to stem from improving microcirculation in the inner ear, particularly within the stria vascularis, which helps to reduce the endolymphatic pressure that characterizes Meniere's. By enhancing blood flow and modulating neurotransmitter activity in the vestibular nuclei, betahistine effectively alleviates the debilitating episodes of dizziness, imbalance, and auditory disturbances experienced by patients. It acts as a weak H1-receptor agonist and a potent H3-receptor antagonist, influencing histamine metabolism and release in the central nervous system, thereby contributing to its anti-vertigo effects and helping to restore vestibular function. This targeted action helps manage the chronic and unpredictable nature of Meniere's disease symptoms.

Uses

Treatment of Meniere's disease.
Relief of vertigo (dizziness).
Management of tinnitus (ringing in the ears).
Improvement of hearing loss associated with Meniere's.

Directions For Use

Take as directed by your physician, usually with or after meals to minimize gastrointestinal upset. Do not crush or chew the tablet.

Benefits

Reduces frequency and severity of vertigo attacks.
Alleviates symptoms of Meniere's disease.
Improves balance and reduces dizziness.
May help reduce tinnitus.
Potentially improves hearing in affected individuals.
Generally well-tolerated with proper use.

Side Effects

Nausea
Indigestion
Headache
Stomach upset
Vomiting
Bloating
Skin rash
Itching
Hives
Abdominal pain
Heartburn
Drowsiness (rare)

Safety Measures

Alcohol - Alcohol may exacerbate dizziness and other central nervous system side effects; use with caution.
Pregnancy - Generally not recommended during pregnancy unless clearly necessary and potential benefits outweigh risks. Consult a doctor.
Breastfeeding - It is unknown if betahistine passes into breast milk. Use with caution and under medical supervision.
Liver - Use with caution in patients with liver impairment; dose adjustment may be necessary.
Kidney - Use with caution in patients with kidney impairment; dose adjustment may be necessary.
Lung - Use with caution in patients with bronchial asthma as it is a histamine analog.

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